Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 11/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 9/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14720137 | 0.82 | KMT2A (0.54) | KMT2ARAB9ANPC1MEN1POLB | |
| SCHEMBL789490 | 0.76 | HDAC3 (0.42) | KMT2ARAB9ANPC1MEN1LMNA | |
| SCHEMBL2299897 | 0.72 | — | — | |
| SCHEMBL2298545 | 0.69 | FPR2 (0.54) | KMT2ARAB9ANPC1MEN1LMNA | |
| SCHEMBL2298347 | 0.68 | KMT2A (0.51) | KMT2ARAB9ANPC1MEN1LMNA | |
| SCHEMBL14720267 | 0.68 | AAK1 (0.45) | RAB9ANPC1LMNASMN1; SMN2POLB | |
| SCHEMBL3824850 | 0.68 | PLG (0.32) | LMNA | |
| SCHEMBL14151538 | 0.68 | KMT2A (0.50) | KMT2ARAB9ANPC1MEN1POLB | |
| SCHEMBL2299286 | 0.66 | KMT2A (0.48) | KMT2ARAB9ANPC1MEN1LMNA | |
| SCHEMBL2295438 | 0.66 | KMT2A (0.48) | KMT2ARAB9ANPC1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011103546-A1 | TRIAZOLONES AS FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2011-08-25 | — | — | WO | disclosed |