Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TACR3 | P29371 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25205463 | 0.86 | DPP4 (0.32) | DPP4 | |
| SCHEMBL14453855 | 0.85 | NAMPT (0.41) | DPP8DPP7SMYD3DPP4 | |
| SCHEMBL22124443 | 0.81 | TACR3 (0.36) | DPP8DPP7POLBSMYD3MEN1 | |
| SCHEMBL104209 | 0.79 | EPHX2 (0.48) | POLBDPP4 | |
| SCHEMBL8263565 | 0.79 | KDM4E (0.48) | MEN1KMT2A | |
| SCHEMBL14720394 | 0.79 | KDM4E (0.48) | MEN1KMT2A | |
| SCHEMBL14003362 | 0.79 | KDM4E (0.48) | MEN1KMT2A | |
| SCHEMBL14720395 | 0.79 | RAB9A (0.45) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL24774506 | 0.79 | EPHX2 (0.39) | POLBKMT2ASMN1; SMN2 | |
| SCHEMBL23568574 | 0.78 | FAAH (0.40) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013028445-A1 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2013-02-28 | — | — | WO | disclosed |