Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14720223 | 0.86 | DPP8 (0.37) | DPP4 | |
| SCHEMBL23992157 | 0.85 | CHRNB2 (0.39) | DPP4 | |
| SCHEMBL12269097 | 0.79 | HSD17B10 (0.33) | DPP4HTR2C | |
| SCHEMBL27807377 | 0.79 | HTR2C (0.35) | HTR2C | |
| SCHEMBL24492465 | 0.79 | JAK3 (0.37) | — | |
| SCHEMBL31348959 | 0.78 | ARG1 (0.33) | — | |
| SCHEMBL24392671 | 0.76 | NAMPT (0.52) | — | |
| SCHEMBL5901263 | 0.74 | MTNR1A (0.42) | — | |
| SCHEMBL14453855 | 0.74 | NAMPT (0.41) | DPP4 | |
| SCHEMBL24774506 | 0.74 | EPHX2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159531-A1 | HTT MODULATORS FOR TREATING HUNTINGTON'S DISEASE | CHDI FOUNDATION, INC. | 2023-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230159531-A1 | HTT MODULATORS FOR TREATING HUNTINGTON'S DISEASE | HTT, HYPK, ATXN2 | DPP4 3603/4885HTR2C 115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.