Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 4/20 | 0.41 |
| ▸ | JAK2 | O60674 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3825100 | 0.87 | HSD11B1 (0.43) | RAB9AHSD11B1JAK1JAK2THRB | |
| SCHEMBL4687962 | 0.82 | RAB9A (0.46) | RAB9AHSD11B1JAK1JAK2MEN1 | |
| SCHEMBL4685564 | 0.81 | RAB9A (0.44) | RAB9AHSD11B1JAK1JAK2THRB | |
| SCHEMBL12760596 | 0.81 | RAB9A (0.44) | RAB9AHSD11B1JAK1JAK2MEN1 | |
| SCHEMBL2012460 | 0.81 | RAB9A (0.44) | RAB9AHSD11B1JAK1JAK2MEN1 | |
| SCHEMBL14720394 | 0.81 | KDM4E (0.48) | RAB9AL3MBTL1HTTMEN1HPGD | |
| SCHEMBL8263565 | 0.81 | KDM4E (0.48) | RAB9AL3MBTL1HTTMEN1HPGD | |
| SCHEMBL14003362 | 0.81 | KDM4E (0.48) | RAB9AL3MBTL1HTTMEN1HPGD | |
| SCHEMBL14405029 | 0.80 | RAB9A (0.47) | RAB9AHSD11B1JAK1JAK2GAA | |
| SCHEMBL4594562 | 0.80 | RAB9A (0.43) | RAB9AHSD11B1JAK1JAK2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013028445-A1 | FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2013-02-28 | — | — | WO | disclosed |