SCHEMBL14720353

SCHEMBL14720353

OC1COCC1c1ccc(C=C2CCN(C3CCC3)CC2)cc1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 17/20 0.36
SRD5A2 P31213 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14720608 0.73 HRH3 (0.43) HRH3SRD5A2
SCHEMBL14720518 0.72 HRH3 (0.46) HRH3
SCHEMBL14721067 0.72 SRD5A2 (0.42) HRH3SRD5A2
SCHEMBL14720734 0.71 SRD5A2 (0.34) HRH3SRD5A2
SCHEMBL14720720 0.71 SRD5A2 (0.58) HRH3SRD5A2
SCHEMBL14720746 0.71 HRH3 (0.38) HRH3
SCHEMBL14720802 0.70 HRH3 (0.39) HRH3SRD5A2
Hydrochloric Acid SCHEMBL14721345 0.70 SRD5A2 (0.57) HRH3SRD5A2
SCHEMBL14720522 0.70 HRH3 (0.39) HRH3SRD5A2
SCHEMBL14721775 0.70 HRH3 (0.43) HRH3SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013027001-A1 COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2013-02-28 WO claimed
EP-2748331-A1 SUSCEPTIBILITY TO SELECTIVE CDK9 INHIBITORS Lead Discovery Center GmbH (DE) 2014-07-02 EP disclosed
WO-2013027001-A1 COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2013-02-28 WO disclosed
WO-2013026890-A1 SUSCEPTIBILITY TO SELECTIVE CDK9 INHIBITORS LEAD DISCOVERY CENTER GMBH (DE) 2013-02-28 WO disclosed
WO-2013027001-A1 COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2013-02-28 WO disclosed