Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | OGA | O60502 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14720948 | 0.83 | SRD5A2 (0.39) | SRD5A2SRD5A1OGA | |
| SCHEMBL31172328 | 0.78 | TSHR (0.50) | SMN1; SMN2ALDH1A1MAPK1TSHRTDP1 | |
| SCHEMBL9061278 | 0.78 | TSHR (0.50) | SMN1; SMN2ALDH1A1MAPK1TSHRTDP1 | |
| SCHEMBL18076482 | 0.72 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL14720707 | 0.71 | SRD5A1 (0.43) | SRD5A2SRD5A1ALDH1A1OGATSHR | |
| SCHEMBL28522830 | 0.70 | APEX1 (0.35) | SMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL28532943 | 0.70 | APEX1 (0.35) | SMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL28522829 | 0.70 | APEX1 (0.35) | SMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL14720524 | 0.69 | PDE4A (0.35) | SMN1; SMN2SRD5A2ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL14731049 | 0.69 | PER2 (0.38) | SMN1; SMN2HTTALDH1A1L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |