Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14720738 | 0.87 | HRH3 (0.42) | HRH3CYP2D6SRD5A2 | |
| SCHEMBL14721216 | 0.82 | HRH3 (0.40) | HRH3CYP2D6SRD5A2 | |
| SCHEMBL14721067 | 0.78 | SRD5A2 (0.42) | HRH3CYP2D6SRD5A2 | |
| SCHEMBL14720838 | 0.78 | SRD5A2 (0.44) | HRH3CYP2D6SRD5A2 | |
| SCHEMBL14721508 | 0.76 | HRH3 (0.38) | HRH3CYP2D6SRD5A2 | |
| SCHEMBL14722348 | 0.76 | HRH3 (0.38) | HRH3CYP2D6SRD5A2 | |
| SCHEMBL14722240 | 0.75 | HRH3 (0.33) | HRH3CYP2D6SRD5A2 | |
| SCHEMBL14720575 | 0.74 | L3MBTL3 (0.51) | HRH3CYP2D6 | |
| SCHEMBL14720972 | 0.74 | HRH3 (0.42) | HRH3CYP2D6SRD5A2 | |
| SCHEMBL14721351 | 0.73 | MCHR1 (0.40) | HRH3CYP2D6SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |