Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MBTD1 | Q05BQ5 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14720710 | 0.88 | HRH3 (0.56) | L3MBTL3L3MBTL1HRH3KDM4E | |
| SCHEMBL14721065 | 0.86 | HRH3 (0.41) | L3MBTL3L3MBTL1HRH3ALDH1A1KDM4E | |
| SCHEMBL14731055 | 0.86 | HRH3 (0.53) | L3MBTL3L3MBTL1HRH3KDM4EKMT2A | |
| SCHEMBL14720643 | 0.85 | OPRM1 (0.41) | L3MBTL3L3MBTL1HRH3MBTD1KMT2A | |
| SCHEMBL14731088 | 0.83 | HRH3 (0.38) | L3MBTL3L3MBTL1HRH3HRH4KDM4E | |
| SCHEMBL14721179 | 0.82 | L3MBTL1 (0.50) | L3MBTL3L3MBTL1HRH3MBTD1CYP2D6 | |
| SCHEMBL14721067 | 0.82 | SRD5A2 (0.42) | L3MBTL3L3MBTL1HRH3ALDH1A1KDM4E | |
| SCHEMBL14720463 | 0.80 | L3MBTL1 (0.47) | L3MBTL1HRH3ALDH1A1KMT2A | |
| SCHEMBL14722538 | 0.79 | POLB (0.36) | L3MBTL3L3MBTL1HRH3 | |
| SCHEMBL14720838 | 0.79 | SRD5A2 (0.44) | L3MBTL3L3MBTL1HRH3ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |