Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4544894 | 0.74 | KMT2A (0.68) | SMN1; SMN2KMT2AHTTTDP1MAPT | |
| SCHEMBL20600116 | 0.74 | KMT2A (0.68) | SMN1; SMN2KMT2AHTTTDP1MAPT | |
| SCHEMBL8424170 | 0.73 | ALDH1A1 (0.49) | SMN1; SMN2KMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL6802995 | 0.72 | LMNA (0.31) | SMN1; SMN2MAPTLMNAPOLB | |
| SCHEMBL8423697 | 0.72 | MMP2 (0.43) | SMN1; SMN2KMT2AHTTALDH1A1LMNA | |
| SCHEMBL7887235 | 0.71 | KMT2A (0.51) | SMN1; SMN2KMT2AHTTTDP1MAPT | |
| SCHEMBL7887233 | 0.71 | KMT2A (0.51) | SMN1; SMN2KMT2AHTTTDP1MAPT | |
| SCHEMBL20599555 | 0.71 | KMT2A (0.75) | SMN1; SMN2KMT2AHTTTDP1MAPT | |
| SCHEMBL8317758 | 0.71 | KMT2A (0.81) | SMN1; SMN2KMT2AHTTTDP1MAPT | |
| SCHEMBL14510071 | 0.70 | KMT2A (0.58) | SMN1; SMN2KMT2AHTTTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |