Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8423588 | 0.90 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AHSD17B10POLB | |
| SCHEMBL8424025 | 0.86 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL8424066 | 0.79 | HPGD (0.43) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL8425464 | 0.75 | S1PR5 (0.44) | ALDH1A1MEN1KMT2ATSHRL3MBTL1 | |
| SCHEMBL8423721 | 0.75 | ALDH1A1 (0.39) | ALDH1A1HSD17B10SMN1; SMN2L3MBTL1 | |
| SCHEMBL8427523 | 0.74 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2AGAAGPR119 | |
| SCHEMBL31151805 | 0.73 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2AGAAHSD17B10 | |
| SCHEMBL14720687 | 0.73 | SMN1; SMN2 (0.42) | ALDH1A1MEN1KMT2AGAAPOLB | |
| SCHEMBL6858259 | 0.68 | ADAM17 (0.47) | — | |
| SCHEMBL8424173 | 0.67 | ALDH1A1 (0.36) | ALDH1A1HSD17B10POLBSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932595-A | ANTIARTHRITIC AGENT; MULTIPLE SCLEROSIS; OSTEOPOROSIS; RESPIRATORY SYSTEM DISORDERS; SKIN DISORDERS; ANTIULCER AGENT | SYNTEX (U.S.A.) INC. (US) | 1999-08-03 | — | — | US | disclosed |