Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 2/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.33 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14721179 | 0.82 | L3MBTL1 (0.50) | SRD5A2HRH3CYP2D6TP53BP1L3MBTL3 | |
| SCHEMBL14720463 | 0.82 | L3MBTL1 (0.47) | SRD5A2HRH3ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL14722442 | 0.80 | GRM2 (0.47) | SRD5A2HRH3SMN1; SMN2GRM2L3MBTL3 | |
| SCHEMBL14720875 | 0.79 | FKBP1A (0.38) | FKBP1ASRD5A2HRH3 | |
| SCHEMBL14720876 | 0.79 | FKBP1A (0.38) | FKBP1ASRD5A2HRH3 | |
| SCHEMBL14720707 | 0.79 | SRD5A1 (0.43) | SRD5A2ALDH1A1LMNACYP2D6GRM2 | |
| SCHEMBL14720854 | 0.78 | HRH3 (0.40) | SRD5A2HRH3GRM2L3MBTL1 | |
| SCHEMBL14721980 | 0.78 | HRH3 (0.43) | SRD5A2HRH3SMN1; SMN2L3MBTL3L3MBTL1 | |
| SCHEMBL14720525 | 0.78 | PDE4A (0.35) | FKBP1ASRD5A2ALDH1A1SMN1; SMN2CYP2D6 | |
| SCHEMBL14720524 | 0.78 | PDE4A (0.35) | FKBP1ASRD5A2ALDH1A1SMN1; SMN2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | claimed |
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |