Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 9/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 9/20 | 0.44 |
| ▸ | TP53BP1 | Q12888 | 3/20 | 0.44 |
| ▸ | MBTD1 | Q05BQ5 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14721516 | 0.86 | MEN1 (0.49) | L3MBTL3L3MBTL1TP53BP1MBTD1HRH3 | |
| SCHEMBL14721178 | 0.83 | HRH3 (0.43) | HRH3HPGDNPC1 | |
| SCHEMBL14720637 | 0.81 | L3MBTL3 (0.62) | L3MBTL3L3MBTL1TP53BP1MBTD1MEN1 | |
| SCHEMBL14721173 | 0.77 | LRRK2 (0.54) | L3MBTL3L3MBTL1TP53BP1MBTD1HRH3 | |
| SCHEMBL14723483 | 0.76 | L3MBTL3 (0.55) | L3MBTL3L3MBTL1TP53BP1MBTD1HRH3 | |
| SCHEMBL14720873 | 0.73 | ALDH1A1 (0.54) | L3MBTL3L3MBTL1TSHRHPGDKMT2A | |
| SCHEMBL14720720 | 0.71 | SRD5A2 (0.58) | L3MBTL3L3MBTL1TP53BP1MBTD1HRH3 | |
| SCHEMBL1085239 | 0.71 | L3MBTL3 (0.67) | L3MBTL3L3MBTL1TP53BP1MBTD1LRRK2 | |
| SCHEMBL14721333 | 0.70 | SRD5A2 (0.52) | L3MBTL3L3MBTL1TP53BP1MBTD1HRH3 | |
| Hydrochloric Acid SCHEMBL14721345 | 0.70 | SRD5A2 (0.57) | L3MBTL3L3MBTL1TP53BP1MBTD1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | claimed |
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |