SCHEMBL1472140

SCHEMBL1472140

CC(C)N(NP(=O)(Cl)CCC#N)C(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20581718 0.75
SCHEMBL8919030 0.72 TSHR (0.31)
SCHEMBL29809963 0.68
SCHEMBL769441 0.67 TSHR (0.33)
SCHEMBL2237800 0.65
SCHEMBL20581719 0.61
SCHEMBL1976528 0.61
SCHEMBL4295740 0.61
SCHEMBL11811303 0.60 TSHR (0.34)
SCHEMBL19859292 0.60 ALDH1A1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11965209-B2 Method for obtaining structural information concerning an encoded molecule and method for selecting compounds NUEVOLUTION A/S (DK) 2024-04-23 US disclosed
US-11702652-B2 Enzymatic encoding methods for efficient synthesis of large libraries NUEVOLUTION A/S (DK) 2023-07-18 US disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-20220205027-A1 METHOD FOR OBTAINING STRUCTURAL INFORMATION CONCERNING AN ENCODED MOLECULE AND METHOD FOR SELECTING COMPOUNDS NUEVOLUTION A/S (DK) 2022-06-30 US disclosed
US-11118215-B2 Method for obtaining structural information concerning an encoded molecule and method for selecting compounds NUEVOLUTION A/S (DK) 2021-09-14 US disclosed
EP-3018206-B1 ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES NUEVOLUTION AS (DK) 2021-08-11 EP disclosed
EP-3305900-B1 ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES NUEVOLUTION AS (DK) 2021-07-21 EP disclosed
US-11001835-B2 Method for the synthesis of a bifunctional complex NUEVOLUTION A/S (DK) 2021-05-11 US disclosed
EP-3299463-B1 ENZYMATIC ENCODING NUEVOLUTION AS (DK) 2020-10-21 EP disclosed
US-10676740-B2 Modified iRNA agents ALNYLAM PHARMACEUTICALS, INC. (US) 2020-06-09 US disclosed
US-6060596-A BIFUNCTIONAL MOLECULES HAVING BOTH A CHEMICAL POLYMER AND AN IDENTIFIER OLIGONUCLEOTIDE SEQUENCE THAT DEFINES THE STRUCTURE OF THE CHEMICAL POLYMER. THE SCRIPPS RESEARCH INSTITUTE (US) 2000-05-09 US disclosed
WO-1999057317-A9 ELECTRONIC METHODS FOR THE DETECTION OF ANALYTES UTILIZING MONOLAYERS CLINICAL MICRO SENSORS INC (US) 2000-02-17 WO disclosed
WO-1999057319-A1 ELECTRONIC DETECTION OF NUCLEIC ACIDS USING MONOLAYERS CLINICAL MICRO SENSORS (US) 1999-11-11 WO disclosed
WO-1999057317-A1 ELECTRONIC METHODS FOR THE DETECTION OF ANALYTES UTILIZING MONOLAYERS CLINICAL MICRO SENSORS, INC. (US) 1999-11-11 WO disclosed
WO-1999037819-A2 AMPLIFICATION OF NUCLEIC ACIDS WITH ELECTRONIC DETECTION CLINICAL MICRO SENSORS, INC. (US) 1999-07-29 WO disclosed
US-5744595-A Propargyl modified nucleosides and nucleotides CHEMGENES CORPORATION (US) 1998-04-28 US disclosed
US-5723598-A Encoded combinatorial chemical libraries THE SCRIPPS RESEARCH INSTITUTE (US) 1998-03-03 US disclosed
US-5573905-A Encoded combinatorial chemical libraries THE SCRIPPS RESEARCH INSTITUTE (US) 1996-11-12 US disclosed
EP-0378652-A1 OLIGONUCLEOTIDE HYBRIDIZATION PROBES AND MEANS FOR THE SYNTHESIS OF THE MOST PREFERRED PROBES WALLAC OY (FI) 1990-07-25 EP disclosed
WO-1990000622-A1 OLIGONUCLEOTIDE HYBRIDIZATION PROBES AND MEANS FOR THE SYNTHESIS OF THE MOST PREFERRED PROBES WALLAC OY (FI) 1990-01-25 WO disclosed