Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4913656 | 0.85 | HRH1 (0.44) | MEN1MAPTTHRBMAPK1HTT | |
| SCHEMBL14722203 | 0.84 | — | — | |
| SCHEMBL14721914 | 0.84 | NUDT1 (0.31) | — | |
| SCHEMBL8027453 | 0.84 | MAPT (0.39) | MEN1MAPTTHRBMAPK1HTT | |
| SCHEMBL14699541 | 0.72 | ALDH1A1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL15900287 | 0.72 | ALDH1A1 (0.32) | MEN1MAPTTHRBKMT2ASMN1; SMN2 | |
| SCHEMBL7168223 | 0.68 | HTR2A (0.30) | — | |
| SCHEMBL7623041 | 0.64 | ALDH1A1 (0.36) | — | |
| SCHEMBL21913839 | 0.63 | SLC6A4 (0.32) | — | |
| SCHEMBL13642931 | 0.62 | MAPT (0.35) | MEN1MAPTTHRBMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026455-A1 | PERMANENTLY POSITIVELY CHARGED ANTIDEPRESSANTS | AARHUS UNIVERSITET (DK) | 2013-02-28 | — | — | WO | disclosed |