Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14721884 | 0.84 | MEN1 (0.34) | MAPTMEN1MAPK1KMT2ATHRB | |
| SCHEMBL4913656 | 0.82 | HRH1 (0.44) | MAPTALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL14722203 | 0.81 | — | — | |
| SCHEMBL14699541 | 0.70 | ALDH1A1 (0.32) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL15900287 | 0.69 | ALDH1A1 (0.32) | MAPTALDH1A1MEN1KMT2ATHRB | |
| SCHEMBL14721914 | 0.69 | NUDT1 (0.31) | — | |
| SCHEMBL21913839 | 0.61 | SLC6A4 (0.32) | — | |
| SCHEMBL9383946 | 0.59 | CA1 (0.35) | CA2 | |
| SCHEMBL7623449 | 0.59 | — | — | |
| SCHEMBL30725973 | 0.57 | MEN1 (0.63) | MAPTALDH1A1MEN1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000064884-A1 | PIPERIDYL-IMIDAZOLE DERIVATIVES, THEIR PREPARATIONS AND THERAPEUTIC USES | NOVO NORDISK A/S (DK) | 2000-11-02 | — | — | WO | disclosed |