Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.37 |
| ▸ | CCR5 | P51681 | 6/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14722527 | 0.94 | PDE4B (0.41) | PDE4BGPR119CCR5RORCMEN1 | |
| SCHEMBL14722369 | 0.85 | CHRM4 (0.42) | — | |
| SCHEMBL14730281 | 0.84 | MAOA (0.32) | — | |
| SCHEMBL12064593 | 0.82 | PDE4B (0.42) | PDE4BGPR119RORCMEN1KMT2A | |
| SCHEMBL14730266 | 0.81 | GPR119 (0.36) | GPR119 | |
| SCHEMBL14730220 | 0.81 | TP53 (0.45) | PDE4BRORCMEN1KMT2A | |
| SCHEMBL470782 | 0.81 | PDE4B (0.42) | PDE4BRORC | |
| SCHEMBL457195 | 0.80 | PDE4B (0.42) | PDE4BGPR119RORC | |
| SCHEMBL14730269 | 0.80 | NTRK1 (0.37) | GPR119CCR5 | |
| SCHEMBL14730168 | 0.79 | GPR119 (0.36) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026587-A1 | 1,4 DISUBSTITUTED PYRROLIDINE - 3 - YL -AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2013-02-28 | — | — | WO | disclosed |