Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 6/20 | 0.31 |
| ▸ | F2R | P25116 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6128140 | 0.92 | GPR119 (0.36) | DPP4DPP8DPP9DPP7F2R | |
| SCHEMBL14730264 | 0.84 | HPGDS (0.38) | MAOBDPP4DPP8DPP9DPP7 | |
| SCHEMBL14722228 | 0.84 | PDE4B (0.42) | — | |
| SCHEMBL14730168 | 0.83 | GPR119 (0.36) | DPP4DPP8DPP7NR1H2KCNH2 | |
| SCHEMBL14730209 | 0.83 | GPR119 (0.31) | NR1H2 | |
| SCHEMBL14730269 | 0.83 | NTRK1 (0.37) | RETF2RNR1H2NPY5RNTRK1 | |
| SCHEMBL458011 | 0.82 | ACACB (0.35) | DPP4DPP8DPP9DPP7RET | |
| SCHEMBL14730335 | 0.81 | DPP4 (0.38) | MAOBDPP4DPP8DPP9DPP7 | |
| SCHEMBL14730224 | 0.81 | NTRK1 (0.35) | MAOAMAOBRETNPY5RNTRK1 | |
| SCHEMBL14723139 | 0.81 | USP30 (0.41) | RETNPY5RNTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026587-A1 | 1,4 DISUBSTITUTED PYRROLIDINE - 3 - YL -AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2013-02-28 | — | — | WO | disclosed |