Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 14/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14723328 | 0.86 | GPR119 (0.39) | — | |
| SCHEMBL6128140 | 0.85 | GPR119 (0.36) | — | |
| SCHEMBL14722228 | 0.85 | PDE4B (0.42) | — | |
| SCHEMBL14730335 | 0.80 | DPP4 (0.38) | — | |
| SCHEMBL14730281 | 0.79 | MAOA (0.32) | — | |
| SCHEMBL14730229 | 0.79 | GPR119 (0.40) | — | |
| SCHEMBL14722672 | 0.79 | GPR119 (0.40) | — | |
| SCHEMBL6128597 | 0.79 | GPR119 (0.40) | — | |
| SCHEMBL14722527 | 0.79 | PDE4B (0.41) | — | |
| SCHEMBL147896 | 0.78 | L3MBTL1 (0.46) | CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026587-A1 | 1,4 DISUBSTITUTED PYRROLIDINE - 3 - YL -AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2013-02-28 | — | — | WO | disclosed |