Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 16/20 | 0.33 |
| ▸ | MAOB | P27338 | 16/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL16632392 | 0.97 | MCL1 (0.35) | MCL1CYP1A2CYP3A4MAPTRAB9A | |
| Bromide SCHEMBL14722531 | 0.95 | MCL1 (0.35) | MCL1CYP1A2CYP3A4MAPTRAB9A | |
| SCHEMBL13066138 | 0.85 | MAPT (0.40) | MCL1CYP1A2CYP3A4MAPTRAB9A | |
| SCHEMBL4542129 | 0.81 | MAPT (0.41) | MCL1CYP1A2CYP3A4MAPTRAB9A | |
| SCHEMBL30549323 | 0.81 | MAOA (0.42) | MCL1CYP1A2CYP3A4MAPTRAB9A | |
| SCHEMBL4539472 | 0.81 | MAOA (0.42) | MCL1CYP1A2CYP3A4MAPTRAB9A | |
| SCHEMBL3159488 | 0.80 | CYP2C9 (0.41) | MCL1CYP1A2CYP3A4MAPTRAB9A | |
| SCHEMBL1615173 | 0.80 | CYP2C9 (0.41) | MCL1CYP1A2CYP3A4MAPTRAB9A | |
| SCHEMBL4538122 | 0.80 | NPC1 (0.40) | MCL1CYP1A2CYP3A4MAPTRAB9A | |
| SCHEMBL28557156 | 0.80 | MAPT (0.42) | MCL1CYP1A2CYP3A4MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10040893-B2 | Polymeric photoinitiators and photoinitiator monomers | COLOPLAST A/S (DK) | 2018-08-07 | — | — | US | claimed |
| US-20150105488-A1 | NOVEL POLYMERIC PHOTOINITIATORS AND PHOTOINITIATOR MONOMERS | COLOPLAST A/S (DK) | 2015-04-16 | — | — | US | claimed |
| US-10040893-B2 | Polymeric photoinitiators and photoinitiator monomers | COLOPLAST A/S (DK) | 2018-08-07 | — | — | US | disclosed |
| EP-2850113-B1 | NOVEL POLYMERIC PHOTOINITIATORS AND PHOTOINITIATOR MONOMERS | COLOPLAST AS (DK) | 2017-08-09 | — | — | EP | disclosed |
| US-9670373-B2 | Polymers comprising photoinitiator moieties and dye moieties | LAMBSON LIMITED (GB) | 2017-06-06 | — | — | US | disclosed |
| US-20150105488-A1 | NOVEL POLYMERIC PHOTOINITIATORS AND PHOTOINITIATOR MONOMERS | COLOPLAST A/S (DK) | 2015-04-16 | — | — | US | disclosed |
| US-20140316060-A1 | Polymers Comprising Photoinitiator Moieties and Dye Moieties | ARKEMA UK LIMITED (GB) | 2014-10-23 | — | — | US | disclosed |
| EP-2744834-A1 | POLYMERS COMPRISING PHOTOINITIATOR MOIETIES AND DYE MOIETIES | Lambson Limited (GB) | 2014-06-25 | — | — | EP | disclosed |
| WO-2013026451-A1 | POLYMERS COMPRISING PHOTOINITIATOR MOIETIES AND DYE MOIETIES | COLOPLAST A/S (DK) | 2013-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150105488-A1 | NOVEL POLYMERIC PHOTOINITIATORS AND PHOTOINITIATOR MONOMERS | ACMSD, AAAS, CLTA | CHRM1 1809/4885MCL1 3959/4885CYP1A2 2635/4885 |
| US-10040893-B2 | Polymeric photoinitiators and photoinitiator monomers | ACMSD, AAAS, PPOX | CHRM1 1691/4885MCL1 3974/4885CYP1A2 1674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.