Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.47 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 5/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14722949 | 1.00 | ALDH1A1 (0.48) | ALDH1A1PKMHTTPTPN7PTPN12 | |
| SCHEMBL14734626 | 0.99 | PTPN7 (0.47) | ALDH1A1PKMHTTPTPN7PTPN12 | |
| SCHEMBL2034913 | 0.95 | PTPN7 (0.50) | ALDH1A1PKMHTTPTPN7PTPN12 | |
| SCHEMBL15862415 | 0.95 | PTPN7 (0.50) | ALDH1A1PKMHTTPTPN7PTPN12 | |
| SCHEMBL4652441 | 0.95 | PTPN7 (0.50) | ALDH1A1PKMHTTPTPN7PTPN12 | |
| SCHEMBL4652572 | 0.95 | PTPN7 (0.50) | ALDH1A1PKMHTTPTPN7PTPN12 | |
| SCHEMBL15862416 | 0.95 | PTPN7 (0.50) | ALDH1A1PKMHTTPTPN7PTPN12 | |
| SCHEMBL2034911 | 0.95 | PTPN7 (0.50) | ALDH1A1PKMHTTPTPN7PTPN12 | |
| SCHEMBL4652445 | 0.95 | PTPN7 (0.50) | ALDH1A1PKMHTTPTPN7PTPN12 | |
| SCHEMBL4652573 | 0.95 | PTPN7 (0.50) | ALDH1A1PKMHTTPTPN7PTPN12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2748280-B1 | PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2016-11-30 | — | — | EP | disclosed |
| US-9366906-B2 | Photoreactive compounds | ROLIC AG (CH) | 2016-06-14 | — | — | US | disclosed |
| US-20140192305-A1 | PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2014-07-10 | — | — | US | disclosed |
| EP-2748280-A1 | PHOTOREACTIVE COMPOUNDS | Rolic AG (CH) | 2014-07-02 | — | — | EP | disclosed |
| WO-2013026691-A1 | PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2013-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140192305-A1 | PHOTOREACTIVE COMPOUNDS | PCNA, CRY1, CRY2 | ALDH1A1 2806/4885PKM 2805/4885HTT 886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.