Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 1/20 | 0.50 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.50 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.43 |
| ▸ | TUBB | P07437 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4652572 | 1.00 | PTPN7 (0.50) | PTPN7PTPN12PTPN22SMN1; SMN2RECQL | |
| SCHEMBL4652573 | 1.00 | PTPN7 (0.50) | PTPN7PTPN12PTPN22SMN1; SMN2RECQL | |
| SCHEMBL15862415 | 1.00 | PTPN7 (0.50) | PTPN7PTPN12PTPN22SMN1; SMN2RECQL | |
| SCHEMBL2034913 | 1.00 | PTPN7 (0.50) | PTPN7PTPN12PTPN22SMN1; SMN2RECQL | |
| SCHEMBL2034911 | 1.00 | PTPN7 (0.50) | PTPN7PTPN12PTPN22SMN1; SMN2RECQL | |
| SCHEMBL15862416 | 1.00 | PTPN7 (0.50) | PTPN7PTPN12PTPN22SMN1; SMN2RECQL | |
| SCHEMBL4652445 | 1.00 | PTPN7 (0.50) | PTPN7PTPN12PTPN22SMN1; SMN2RECQL | |
| SCHEMBL4651481 | 0.99 | PTPN7 (0.51) | PTPN7PTPN12PTPN22SMN1; SMN2RECQL | |
| SCHEMBL4651477 | 0.99 | PTPN7 (0.51) | PTPN7PTPN12PTPN22SMN1; SMN2RECQL | |
| SCHEMBL14722950 | 0.95 | ALDH1A1 (0.48) | PTPN7PTPN12PTPN22SMN1; SMN2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2748280-B1 | PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2016-11-30 | — | — | EP | disclosed |
| EP-2748280-B1 | PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2016-11-30 | — | — | EP | disclosed |
| US-9366906-B2 | Photoreactive compounds | ROLIC AG (CH) | 2016-06-14 | — | — | US | disclosed |
| US-9366906-B2 | Photoreactive compounds | ROLIC AG (CH) | 2016-06-14 | — | — | US | disclosed |
| US-20140192305-A1 | PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2014-07-10 | — | — | US | disclosed |
| US-20140192305-A1 | PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2014-07-10 | — | — | US | disclosed |
| WO-2013026691-A1 | PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2013-02-28 | — | — | WO | disclosed |
| EP-1975687-A1 | Method of uniform and defect free liquid crystal aligning layers | Rolic AG (CH) | 2008-10-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140192305-A1 | PHOTOREACTIVE COMPOUNDS | PCNA, CRY1, CRY2 | PTPN7 2421/4885PTPN12 2058/4885PTPN22 2462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.