Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF20A | O95235 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.40 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14722497 | 1.00 | KIF20A (0.43) | KIF20ARAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL14722884 | 0.94 | KIF20A (0.47) | KIF20ARAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL14722730 | 0.94 | KIF20A (0.47) | KIF20ARAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL14723021 | 0.87 | CASP3 (0.43) | KIF20ARAB9ANPC1KDM4EMAPT | |
| SCHEMBL14723023 | 0.87 | CASP3 (0.43) | KIF20ARAB9ANPC1KDM4EMAPT | |
| SCHEMBL15869814 | 0.86 | KIF20A (0.45) | KIF20ARAB9ASMN1; SMN2NPC1KDM4E | |
| SCHEMBL14722549 | 0.84 | PTPN7 (0.45) | KIF20ARAB9ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL14722331 | 0.84 | PTPN7 (0.45) | KIF20ARAB9ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL15862476 | 0.84 | PTPN7 (0.45) | KIF20ARAB9ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL14722329 | 0.84 | PTPN7 (0.45) | KIF20ARAB9ASMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2748280-B1 | PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2016-11-30 | — | — | EP | disclosed |
| EP-2748280-B1 | PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2016-11-30 | — | — | EP | disclosed |
| US-9366906-B2 | Photoreactive compounds | ROLIC AG (CH) | 2016-06-14 | — | — | US | disclosed |
| US-9366906-B2 | Photoreactive compounds | ROLIC AG (CH) | 2016-06-14 | — | — | US | disclosed |
| US-9366906-B2 | Photoreactive compounds | ROLIC AG (CH) | 2016-06-14 | — | — | US | disclosed |
| US-20140192305-A1 | PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2014-07-10 | — | — | US | disclosed |
| US-20140192305-A1 | PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2014-07-10 | — | — | US | disclosed |
| US-20140192305-A1 | PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2014-07-10 | — | — | US | disclosed |
| EP-2748280-A1 | PHOTOREACTIVE COMPOUNDS | Rolic AG (CH) | 2014-07-02 | — | — | EP | disclosed |
| WO-2013026691-A1 | PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2013-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140192305-A1 | PHOTOREACTIVE COMPOUNDS | PCNA, CRY1, CRY2 | KIF20A 727/4885RAB9A 1182/4885SMN1; SMN2 4869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.