SCHEMBL14723346

SCHEMBL14723346

CC(C)(C)OC(=O)N(C1CC1)C1CCN(c2nc(C3(O)CC3)no2)CC1

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 18/20 0.39
KDM1A O60341 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14723457 0.83 KDM1A (0.39) GPR119KDM1A
SCHEMBL14723590 0.82 GPR119 (0.40) GPR119
SCHEMBL14722740 0.78 GPR119 (0.40) GPR119
SCHEMBL14723557 0.72 GPR119 (0.39) GPR119
SCHEMBL21626611 0.68 GPR119 (0.40) GPR119
SCHEMBL14723459 0.68 ALOX5AP (0.37) GPR119
SCHEMBL14723019 0.67 GPR119 (0.38) GPR119
SCHEMBL14722248 0.67 GPR119 (0.38) GPR119
SCHEMBL16580729 0.66 GPR119 (0.50) GPR119
SCHEMBL29532134 0.65 HRH3 (0.42) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013026587-A1 1,4 DISUBSTITUTED PYRROLIDINE - 3 - YL -AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS PROSIDION LIMITED (GB) 2013-02-28 WO disclosed