Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | BMP1 | P13497 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14723590 | 0.80 | GPR119 (0.40) | GPR119 | |
| SCHEMBL14723346 | 0.78 | GPR119 (0.39) | GPR119 | |
| SCHEMBL31706122 | 0.74 | L3MBTL1 (0.48) | NPC1LMNAMAPTHTT | |
| SCHEMBL17100754 | 0.73 | PLAT (0.42) | MMP2BMP1NPC1LMNAMAPT | |
| SCHEMBL6128595 | 0.70 | GPR119 (0.39) | GPR119 | |
| SCHEMBL14723557 | 0.69 | GPR119 (0.39) | GPR119 | |
| SCHEMBL14722248 | 0.69 | GPR119 (0.38) | GPR119 | |
| SCHEMBL1935158 | 0.68 | SLC26A6 (0.36) | MMP2BMP1 | |
| SCHEMBL21679076 | 0.68 | MMP2 (0.38) | MMP2BMP1MAPT | |
| SCHEMBL21626611 | 0.66 | GPR119 (0.40) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026587-A1 | 1,4 DISUBSTITUTED PYRROLIDINE - 3 - YL -AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2013-02-28 | — | — | WO | disclosed |