Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRB | P28702 | 2/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 7/20 | 0.38 |
| ▸ | RARA | P10276 | 6/20 | 0.38 |
| ▸ | RARG | P13631 | 6/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | RORC | P51449 | 2/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14723352 | 1.00 | RXRB (0.43) | RXRBRXRARARBRARARARG | |
| SCHEMBL31589793 | 0.93 | RXRB (0.42) | RXRBRXRARARBRARARARG | |
| SCHEMBL30821396 | 0.93 | RXRB (0.42) | RXRBRXRARARBRARARARG | |
| SCHEMBL14721993 | 0.93 | RXRB (0.42) | RXRBRXRARARBRARARARG | |
| SCHEMBL14721995 | 0.93 | RXRB (0.42) | RXRBRXRARARBRARARARG | |
| SCHEMBL29168436 | 0.92 | RXRB (0.46) | RXRBRXRARARBRARARARG | |
| SCHEMBL20492267 | 0.91 | MKNK1 (0.36) | RXRBRXRAPDK2CA1CA2 | |
| SCHEMBL30309306 | 0.91 | MKNK1 (0.36) | RXRBRXRAPDK2CA1CA2 | |
| SCHEMBL2014009 | 0.91 | RXRB (0.41) | RXRBRXRARARBRARARARG | |
| SCHEMBL12274098 | 0.91 | RXRB (0.41) | RXRBRXRARARBRARARARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026089-B | Isoxazoline substituted benzamides and analogs as pesticides | 先正达参股股份有限公司 | 2021-10-22 | — | — | CN | disclosed |
| EP-3353171-B1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDES AND ANALOGUES AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2021-09-15 | — | — | EP | disclosed |
| US-10588317-B2 | Isoxazoline-substituted benzamides and analogues as insecticides | SYNGENTA PARTICIPATIONS AG (CH) | 2020-03-17 | — | — | US | disclosed |
| US-20180255780-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDES AND ANALOGUES AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-09-13 | — | — | US | disclosed |
| EP-3353171-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDES AND ANALOGUES AS INSECTICIDES | Syngenta Participations AG (CH) | 2018-08-01 | — | — | EP | disclosed |
| EP-2748155-B1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-12-20 | — | — | EP | disclosed |
| EP-2748155-B1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-12-20 | — | — | EP | disclosed |
| WO-2017050922-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDES AND ANALOGUES AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-03-30 | — | — | WO | disclosed |
| US-9247740-B2 | Isoxazoline derivatives as insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2016-02-02 | — | — | US | disclosed |
| US-9247740-B2 | Isoxazoline derivatives as insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2016-02-02 | — | — | US | disclosed |
| US-20140206606-A1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-07-24 | — | — | US | disclosed |
| US-20140206606-A1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-07-24 | — | — | US | disclosed |
| EP-2748155-A1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2014-07-02 | — | — | EP | disclosed |
| WO-2013026695-A1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-02-28 | — | — | WO | disclosed |
| WO-2013026695-A1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-02-28 | — | — | WO | disclosed |
| WO-2013026931-A1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140206606-A1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS | CHRM1, CHRM3, CHRM2 | RXRB 1867/4885RXRA 1816/4885RARB 4645/4885 |
| US-20180255780-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDES AND ANALOGUES AS INSECTICIDES | ACHE, CHRM1, NIT2 | RXRB 2591/4885RXRA 1905/4885RARB 3028/4885 |
| US-10588317-B2 | Isoxazoline-substituted benzamides and analogues as insecticides | ACHE, CHRM1, NIT2 | RXRB 2591/4885RXRA 1905/4885RARB 3028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.