Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRB | P28702 | 2/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 6/20 | 0.37 |
| ▸ | RARA | P10276 | 5/20 | 0.37 |
| ▸ | RARG | P13631 | 5/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 2/20 | 0.32 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.31 |
| ▸ | IL2 | P60568 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14721993 | 1.00 | RXRB (0.42) | RXRBRXRARARBRARARARG | |
| SCHEMBL30821396 | 1.00 | RXRB (0.42) | RXRBRXRARARBRARARARG | |
| SCHEMBL14723349 | 0.93 | RXRB (0.43) | RXRBRXRARARBRARARARG | |
| SCHEMBL14723352 | 0.93 | RXRB (0.43) | RXRBRXRARARBRARARARG | |
| SCHEMBL18670608 | 0.92 | RXRA (0.35) | RXRBRXRACA1CA2IL2 | |
| SCHEMBL18669129 | 0.92 | RXRA (0.35) | RXRBRXRACA1CA2IL2 | |
| SCHEMBL29168436 | 0.91 | RXRB (0.46) | RXRBRXRARARBRARARARG | |
| SCHEMBL20492189 | 0.91 | GPR52 (0.35) | RXRBRXRACA1CA2PDK2 | |
| SCHEMBL30657024 | 0.91 | GPR52 (0.35) | RXRBRXRACA1CA2PDK2 | |
| SCHEMBL20547572 | 0.91 | PDK2 (0.40) | RXRBRXRACA1CA2PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12628827-B2 | Isoxazoline compounds and their use as pest control agents | PI INDUSTRIES LIMITED (IN) | 2026-05-19 | — | — | US | disclosed |
| US-12564193-B2 | Isoxazoline-substituted benzamide derivative, and preparation method therefor and use thereof | SHANDONG UNITED PESTICIDE INDUSTRY CO., LTD. (CN) | 2026-03-03 | — | — | US | disclosed |
| US-20250380697-A1 | ISOXAZOLINE DERIVATIVE COMPOUND AND INSECTICIDAL COMPOSITION COMPRISING SAME | KYUNG NONG CORPORATION (KR) | 2025-12-18 | — | — | US | disclosed |
| EP-4159732-B1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | SHANDONG UNITED PESTICIDE IND CO LTD (CN) | 2025-10-15 | — | — | EP | disclosed |
| WO-2025108463-A1 | ISOXAZOLINE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 山东康乔生物科技有限公司 | 2025-05-30 | — | — | WO | disclosed |
| CN-120040365-A | Isoxazoline compound and preparation method and application thereof | 山东康乔生物科技有限公司 | 2025-05-27 | — | — | CN | disclosed |
| CN-118930531-A | Isoxazoline derivative and preparation method and application thereof | 山东省联合农药工业有限公司 | 2024-11-12 | — | — | CN | disclosed |
| WO-2024175572-A1 | PROCESS FOR THE PREPARATION OF ISOXAZOLINE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2024-08-29 | — | — | WO | disclosed |
| WO-2024120137-A1 | SUBSTITUTED BENZAMIDE ISOXAZOLINE DERIVATIVE OR AGROCHEMICALLY ACCEPTABLE SALT THEREOF, COMPOSITION, AND USE THEREOF | 海利尔药业集团股份有限公司 | 2024-06-13 | — | — | WO | disclosed |
| CN-118076600-A | Compound containing five-membered heterocycle, and preparation method and application thereof | 青岛康乔药业集团有限公司 | 2024-05-24 | — | — | CN | disclosed |
| US-20150126523-A1 | ANTIPARISITIC AND PESTICIDAL ISOXAZOLINE COMPOUNDS | MERIAL LIMITED (US) | 2015-05-07 | — | — | US | disclosed |
| US-20150126523-A1 | ANTIPARISITIC AND PESTICIDAL ISOXAZOLINE COMPOUNDS | MERIAL LIMITED (US) | 2015-05-07 | — | — | US | disclosed |
| EP-2782449-A1 | ISOXAZOLINE DERIVATIVES USED IN THE CONTROL OF ECTOPARASITES | Anacor Pharmaceuticals, Inc. (US) | 2014-10-01 | — | — | EP | disclosed |
| US-20140206606-A1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-07-24 | — | — | US | disclosed |
| EP-2748155-A1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2014-07-02 | — | — | EP | disclosed |
| US-8546357-B2 | Boron-containing small molecules for controlling ectoparasites | ELI LILLY AND COMPANY (US) | 2013-10-01 | — | — | US | disclosed |
| WO-2013078071-A1 | ISOXAZOLINE DERIVATIVES USED IN THE CONTROL OF ECTOPARASITES | ELI LILLY AND COMPANY (US) | 2013-05-30 | — | — | WO | disclosed |
| US-20130131017-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2013-05-23 | — | — | US | disclosed |
| WO-2013026695-A1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-02-28 | — | — | WO | disclosed |
| WO-2013026931-A1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12564193-B2 | Isoxazoline-substituted benzamide derivative, and preparation method therefor and use thereof | CYP4F11, CYP4Z1, CYP4X1 | RXRB 2159/4885RXRA 1520/4885RARB 4157/4885 |
| US-20140206606-A1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS | CHRM1, CHRM3, CHRM2 | RXRB 1867/4885RXRA 1816/4885RARB 4645/4885 |
| US-12628827-B2 | Isoxazoline compounds and their use as pest control agents | HCN1, CBR3, SCN1B | RXRB 1423/4885RXRA 1106/4885RARB 3352/4885 |
| US-20130131017-A1 | BORON-CONTAINING SMALL MOLECULES | BCL6B, BCL6, RB1 | RXRB 1224/4885RXRA 3026/4885RARB 1075/4885 |
| US-20250380697-A1 | ISOXAZOLINE DERIVATIVE COMPOUND AND INSECTICIDAL COMPOSITION COMPRISING SAME | VIP, CASP7, CYP4X1 | RXRB 849/4885RXRA 1013/4885RARB 3103/4885 |
| US-20150126523-A1 | ANTIPARISITIC AND PESTICIDAL ISOXAZOLINE COMPOUNDS | ACHE, PRDX1, CHRM1 | RXRB 1792/4885RXRA 2191/4885RARB 3907/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.