Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | DGKA | P23743 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PAM | P19021 | 2/20 | 0.40 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15345844 | 0.90 | DGKA (0.43) | MAPTDGKALMNAKDM4EDUSP3 | |
| SCHEMBL26442 | 0.87 | GPR84 (0.52) | DGKALMNAMGLLTSHRGPR84 | |
| SCHEMBL2955658 | 0.86 | DGKA (0.43) | MAPTDGKALMNAKDM4EDUSP3 | |
| Adipic Acid SCHEMBL28895995 | 0.85 | TSHR (0.50) | DGKALMNAMGLLTSHRGPR84 | |
| Ammonia Solution, Strong SCHEMBL7134656 | 0.85 | GPR84 (0.50) | DGKALMNAMGLLTSHRGPR84 | |
| SCHEMBL4159638 | 0.85 | GPR84 (0.56) | DGKALMNAMEN1KMT2AMGLL | |
| Water SCHEMBL11810660 | 0.85 | GPR84 (0.50) | DGKALMNAMGLLTSHRGPR84 | |
| SCHEMBL176409 | 0.85 | GPR84 (0.56) | DGKALMNAMEN1KMT2AMGLL | |
| Ethylene Glycol SCHEMBL4909367 | 0.85 | GPR84 (0.50) | DGKALMNAMGLLTSHRGPR84 | |
| SCHEMBL729520 | 0.85 | GPR84 (0.56) | DGKALMNAMEN1KMT2AMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1971427-A1 | VISIBLE LIGHT CURING SYSTEMS, METHODS FOR REDUCING HEALTH RISKS TO INDIVIDUALS EXPOSED TO SYSTEMS DESIGNED TO CURE CURABLE COMPOSITIONS BY EXPOSURE TO RADIATION, METHODS FOR BONDING SUBSTRATES AND VISIBLE LIGHT CURING COMPOSITIONS | Henkel Corporation (US) | 2008-09-24 | — | — | EP | claimed |
| WO-2007078851-A1 | VISIBLE LIGHT CURING SYSTEMS, METHODS FOR REDUCING HEALTH RISKS TO INDIVIDUALS EXPOSED TO SYSTEMS DESIGNED TO CURE CURABLE COMPOSITIONS BY EXPOSURE TO RADIATION, METHODS FOR BONDING SUBSTRATES AND VISIBLE LIGHT CURING COMPOSITIONS | HENKEL CORPORATION (US) | 2007-07-12 | — | — | WO | claimed |
| US-20070138411-A1 | Visible light curing systems, methods for reducing health risks to individuals exposed to systems designed to cure curable compositions by exposure to radiation, methods for bonding substrates and visible light curing compositions | HENKEL CORPORATION | 2007-06-21 | — | — | US | claimed |
| WO-2006083343-A1 | VINYL ETHER/ACRYLATE BLOCK RESINS, COMPOSITIONS AND METHODS OF MAKING SAME | HENKEL CORPORATION (US) | 2006-08-10 | — | — | WO | claimed |
| CN-112824978-A | Cleaning blade, process cartridge, and image forming apparatus | 株式会社理光 | 2021-05-21 | — | — | CN | disclosed |
| US-9994690-B2 | Cellular porous monoliths containing condensed tannins | UNIVERSITE DE LORRAINE (FR) | 2018-06-12 | — | — | US | disclosed |
| EP-2890555-B1 | CELLULAR POROUS MONOLITHS CONTAINING CONDENSED TANNINS | UNIV LORRAINE (FR) | 2016-09-28 | — | — | EP | disclosed |
| US-20150274921-A1 | CELLULAR POROUS MONOLITHS CONTAINING CONDENSED TANNINS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2015-10-01 | — | — | US | disclosed |
| EP-2890555-A1 | CELLULAR POROUS MONOLITHS CONTAINING CONDENSED TANNINS | Université de Lorraine (FR) | 2015-07-08 | — | — | EP | disclosed |
| WO-2014033124-A1 | CELLULAR POROUS MONOLITHS CONTAINING CONDENSED TANNINS | UNIVERSITE DE LORRAINE (FR) | 2014-03-06 | — | — | WO | disclosed |
| US-7915319-B2 | Visible light curing systems, methods for reducing health risks to individuals exposed to systems designed to cure curable compositions by exposure to radiation, methods for bonding substrates and visible light curing compositions | HENKEL CORPORATION (US) | 2011-03-29 | — | — | US | disclosed |
| EP-1971427-A1 | VISIBLE LIGHT CURING SYSTEMS, METHODS FOR REDUCING HEALTH RISKS TO INDIVIDUALS EXPOSED TO SYSTEMS DESIGNED TO CURE CURABLE COMPOSITIONS BY EXPOSURE TO RADIATION, METHODS FOR BONDING SUBSTRATES AND VISIBLE LIGHT CURING COMPOSITIONS | Henkel Corporation (US) | 2008-09-24 | — | — | EP | disclosed |
| US-20080139687-A1 | Vinyl Ether/Acrylate Block Resins, Compositions and Methods of Making Same | HENKEL CORPORATION (US) | 2008-06-12 | — | — | US | disclosed |
| WO-2007078851-A1 | VISIBLE LIGHT CURING SYSTEMS, METHODS FOR REDUCING HEALTH RISKS TO INDIVIDUALS EXPOSED TO SYSTEMS DESIGNED TO CURE CURABLE COMPOSITIONS BY EXPOSURE TO RADIATION, METHODS FOR BONDING SUBSTRATES AND VISIBLE LIGHT CURING COMPOSITIONS | HENKEL CORPORATION (US) | 2007-07-12 | — | — | WO | disclosed |
| US-20070138411-A1 | Visible light curing systems, methods for reducing health risks to individuals exposed to systems designed to cure curable compositions by exposure to radiation, methods for bonding substrates and visible light curing compositions | HENKEL CORPORATION | 2007-06-21 | — | — | US | disclosed |
| WO-2006083343-A1 | VINYL ETHER/ACRYLATE BLOCK RESINS, COMPOSITIONS AND METHODS OF MAKING SAME | HENKEL CORPORATION (US) | 2006-08-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150274921-A1 | CELLULAR POROUS MONOLITHS CONTAINING CONDENSED TANNINS | HES1, PITRM1, TAS2R46 | MAPT 2753/4885DGKA 2840/4885LMNA 2339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.