SCHEMBL1472399

SCHEMBL1472399

O=S(=O)(O)c1ccccc1/N=N/c1c(S(=O)(=O)O)cc2cc(S(=O)(=O)O)c(/N=N/c3ccccc3S(=O)(=O)O)c(O)c2c1O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.62
MAPK1 P28482 2/20 0.61
CYP2C9 P11712 1/20 0.61
DNASE1L3 Q13609 1/20 0.61
PRMT1 Q99873 1/20 0.58
FUT8 Q9BYC5 1/20 0.57
ENPP2 Q13822 3/20 0.52
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
HTT P42858 1/20 0.50
ALDH1A1 P00352 2/20 0.48
HIF1A Q16665 1/20 0.48
PHLPP2 Q6ZVD8 2/20 0.47
MPL P40238 3/20 0.46
CTRC Q99895 1/20 0.46
THRB P10828 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
NSD2 O96028 1/20 0.42
MMP14 P50281 1/20 0.42
CASP6 P55212 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1472408 1.00 CYP1A2 (0.62) CYP1A2MAPK1CYP2C9DNASE1L3PRMT1
SCHEMBL29050868 0.99 CYP1A2 (0.61) CYP1A2MAPK1CYP2C9DNASE1L3PRMT1
SCHEMBL4939211 0.99 CYP1A2 (0.65) CYP1A2MAPK1CYP2C9DNASE1L3PRMT1
SCHEMBL29050875 0.91 CYP1A2 (0.54) CYP1A2MAPK1CYP2C9DNASE1L3PRMT1
SCHEMBL6229887 0.86 CYP1A2 (0.74) CYP1A2MAPK1CYP2C9DNASE1L3PRMT1
SCHEMBL13763680 0.86 CYP1A2 (0.64) CYP1A2MAPK1CYP2C9DNASE1L3PRMT1
SCHEMBL8453667 0.86 CYP1A2 (0.74) CYP1A2MAPK1CYP2C9DNASE1L3PRMT1
SCHEMBL7586572 0.86 CYP1A2 (0.64) CYP1A2MAPK1CYP2C9DNASE1L3PRMT1
SCHEMBL7586578 0.86 CYP1A2 (0.64) CYP1A2MAPK1CYP2C9DNASE1L3PRMT1
SCHEMBL8771585 0.84 ENPP2 (0.57) CYP1A2MAPK1CYP2C9DNASE1L3PRMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8294282-B2 Semiconductor device and adhesive sheet KABUSHIKI KAISHA TOSHIBA (JP) 2012-10-23 US disclosed
US-20110068480-A1 SEMICONDUCTOR DEVICE AND ADHESIVE SHEET TOSHIBA MEMORY CORPORATION (JP) 2011-03-24 US disclosed
US-7264932-B2 Nuclease inhibitor cocktail APPLERA CORPORATION (US) 2007-09-04 US disclosed
US-20070032418-A1 Small-molecule inhibitors of angiogenin and rnases and in vivo and in vitro methods of using same AMBION, INC (US) 2007-02-08 US disclosed
US-6498132-B2 SURFACE TREATMENT COMPOSITION COMPRISES A COMPLEXING AGENT AS A METAL DEPOSITION PREVENTIVE COMPRISING ATLEAST ONE AROMATIC HYDROCARBON RING CONTAINING HYDROXY OR O-GROUP DIRECTLY ATTACHED WITH RING CARBON AND A SECOND COMPLEXING AGENT MITSUBISHI CHEMICAL CORPORATION (JP) 2002-12-24 US disclosed
US-20020045556-A1 Method for treating surface of substrate and surface treatment composition used for the same MITSUBISHI CHEMICAL CORPORATION (JP) 2002-04-18 US disclosed
US-5885362-A APPLYING TO SURFACE A COMPOSITION COMPRISING A LIQUID MEDIUM AND AT LEAST ONE COMPLEXING AGENT, FOR EXAMPLE ETHYLENEDIAMINEDIORTHOHYDROXYPHENYLACETIC ACID MITSUBISHI CHEMICAL CORPORATION (JP) 1999-03-23 US disclosed
US-5790627-A Method and apparatus for observing a specimen using an X-ray microscope RESEARCH DEVELOPMENT CORP. (JP) 1998-08-04 US disclosed
EP-0789071-A1 METHOD FOR TREATING SURFACE OF SUBSTRATE AND SURFACE TREATMENT COMPOSITION THEREFOR MITSUBISHI CHEMICAL CORPORATION (JP) 1997-08-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070032418-A1 Small-molecule inhibitors of angiogenin and rnases and in vivo and in vitro methods of using same RNASE1, RNASEH1, RNASEL CYP1A2 4375/4885MAPK1 3346/4885CYP2C9 4801/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.