Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 5/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3853216 | 0.87 | SIRT1 (0.31) | — | |
| SCHEMBL18348160 | 0.71 | PGR (0.44) | — | |
| SCHEMBL20238499 | 0.70 | ESR2 (0.49) | ERN1 | |
| SCHEMBL29588325 | 0.70 | ESR2 (0.49) | ERN1 | |
| SCHEMBL17863581 | 0.70 | MAPK1 (0.37) | — | |
| SCHEMBL9946125 | 0.68 | ALDH1A1 (0.30) | — | |
| SCHEMBL4498280 | 0.68 | LPL (0.47) | — | |
| SCHEMBL9946120 | 0.66 | HTR2A (0.37) | — | |
| SCHEMBL459167 | 0.65 | SRC (0.47) | ERN1 | |
| SCHEMBL3855480 | 0.65 | SMN1; SMN2 (0.44) | ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836174-B1 | ARYL NITROGEN-CONTAINING BICYCLIC COMPOUNDS AND THEIR USE AS KINASE INHIBITORS | AMGEN INC (US) | 2013-02-27 | — | — | EP | disclosed |