Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCK | P27707 | 11/20 | 0.53 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.40 |
| ▸ | FEN1 | P39748 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13529716 | 0.85 | DCK (0.53) | DCKALDH1A1ALOX5APFEN1 | |
| SCHEMBL17011544 | 0.82 | DCK (0.44) | DCKMEN1KMT2AALOX5APFEN1 | |
| SCHEMBL13530242 | 0.82 | DCK (0.53) | DCKMAP4K4ALDH1A1MEN1KMT2A | |
| SCHEMBL13529746 | 0.80 | DCK (0.57) | DCKALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL13764971 | 0.78 | DCK (0.44) | DCKMAP4K4MEN1KMT2AALOX5AP | |
| SCHEMBL13530435 | 0.77 | MPO (0.45) | DCKALDH1A1 | |
| SCHEMBL13529938 | 0.74 | LMNA (0.41) | DCKALDH1A1CYP1A2CYP2C9HPGD | |
| SCHEMBL13529827 | 0.74 | ADRA2A (0.40) | DCKALOX5APFEN1 | |
| SCHEMBL28669539 | 0.73 | ALOX5AP (0.51) | MAP4K4SMN1; SMN2ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL16303088 | 0.72 | DCK (0.38) | DCKSMN1; SMN2ALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2562175-A1 | 5-FLUORO PYRIMIDINE DERIVATIVES AS FUNGICIDES | Dow AgroSciences LLC (US) | 2013-02-27 | — | — | EP | disclosed |