SCHEMBL14725239

SCHEMBL14725239

c1ccc(-c2ccncn2)c(-c2ccc3c(c2)c2ccc(-c4ccccc4-c4ccncn4)cc2c2ccc(-c4ccccc4-c4ccncn4)cc32)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPK9 P45984 3/20 0.40
▸ MAP4K4 O95819 2/20 0.40
▸ EGFR P00533 2/20 0.40
▸ FRK P42685 2/20 0.40
▸ CSNK1A1 P48729 2/20 0.40
▸ DCLK1 O15075 1/20 0.40
▸ PRKD3 O94806 1/20 0.40
▸ PRKACA P17612 1/20 0.40
▸ FLT3 P36888 1/20 0.40
▸ GSK3B P49841 1/20 0.40
▸ MINK1 Q8N4C8 1/20 0.40
▸ SLK Q9H2G2 1/20 0.40
▸ CLK4 Q9HAZ1 1/20 0.40
▸ MAP4K5 Q9Y4K4 1/20 0.40
▸ MAPK14 Q16539 2/20 0.39
▸ MAPK10 P53779 1/20 0.39
▸ FEN1 P39748 6/20 0.38
▸ ALOX5AP P20292 5/20 0.38
▸ TGFBR1 P36897 1/20 0.37
▸ MAPK13 O15264 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17426588 0.84 CYP2D6 (0.42) MAPK9MAP4K4EGFRFRKCSNK1A1
SCHEMBL10601314 0.82 MAPK9 (0.43) MAPK9MAP4K4EGFRFRKCSNK1A1
SCHEMBL27928941 0.80 CHRNB2 (0.50) MAPK9MAP4K4EGFRFRKCSNK1A1
SCHEMBL13866631 0.79 KDM4E (0.45) FEN1ALOX5APTGFBR1GRM5
SCHEMBL28135245 0.78 MAPK9 (0.55) MAPK9MAP4K4EGFRFRKCSNK1A1
SCHEMBL28135246 0.78 RPS6KA3 (0.50) MAPK9MAP4K4EGFRFRKCSNK1A1
SCHEMBL28135256 0.78 MAPK14 (0.40) MAPK9MAP4K4EGFRFRKCSNK1A1
SCHEMBL28135250 0.78 MAOB (0.41) MAPK9MAPK14MAPK13RAF1MAPK12
SCHEMBL14725237 0.77 MAPK9 (0.38) MAPK9MAP4K4EGFRFRKCSNK1A1
SCHEMBL28135261 0.74 ADRB2 (0.46) MAPK9MAP4K4EGFRFRKCSNK1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240026217-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Novel Organic Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-01-25 — — US disclosed
US-20240026217-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Novel Organic Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2024-01-25 — — US disclosed
US-11773321-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and novel organic compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2023-10-03 — — US disclosed
US-11773321-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and novel organic compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2023-10-03 — — US disclosed
US-20210277305-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Novel Organic Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2021-09-09 — — US disclosed
US-11008510-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and novel organic compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2021-05-18 — — US disclosed
US-20170253796-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Novel Organic Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-09-07 — — US disclosed
US-20170253796-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Novel Organic Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-09-07 — — US disclosed
US-9663711-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and novel organic compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-05-30 — — US disclosed
US-9663711-B2 Light-emitting element, light-emitting device, electronic device, lighting device, and novel organic compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-05-30 — — US disclosed
US-20130048964-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Novel Organic Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2013-02-28 — — US disclosed
US-20130048964-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Novel Organic Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2013-02-28 — — US disclosed
WO-2013027846-A1 LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, LIGHTING DEVICE, AND NOVEL ORGANIC COMPOUND SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-02-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130048964-A1 Light-Emitting Element, Light-Emitting Device, Electronic Device, Lighting Device, and Novel Organic Compound LAGE3, LEF1, PUM2 MAPK9 1590/4885MAP4K4 2643/4885EGFR 3339/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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