Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | MAOA | P21397 | 2/20 | 0.58 |
| ▸ | MAOB | P27338 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL6746153 | 0.84 | CA2 (0.58) | ALDH1A1KMT2AMEN1SMN1; SMN2POLB | |
| SCHEMBL146561 | 0.84 | CA2 (0.58) | ALDH1A1KMT2AMEN1SMN1; SMN2POLB | |
| SCHEMBL3396831 | 0.82 | ALDH1A1 (0.85) | ALDH1A1PTPN7KMT2AGAALMNA | |
| Hydrochloric Acid SCHEMBL5069950 | 0.82 | CA2 (0.56) | ALDH1A1KMT2AMEN1SMN1; SMN2POLB | |
| Methane SCHEMBL3339448 | 0.82 | CA2 (0.56) | ALDH1A1KMT2AMEN1SMN1; SMN2ACP1 | |
| SCHEMBL28176614 | 0.82 | CA2 (0.56) | ALDH1A1KMT2AMEN1SMN1; SMN2POLB | |
| Ammonia Solution, Strong SCHEMBL4592850 | 0.82 | KEAP1 (0.56) | ALDH1A1KMT2AMEN1SMN1; SMN2ACP1 | |
| SCHEMBL3213812 | 0.82 | CA2 (0.56) | ALDH1A1KMT2AMEN1SMN1; SMN2POLB | |
| SCHEMBL29756025 | 0.82 | CA2 (0.56) | ALDH1A1KMT2AMEN1SMN1; SMN2ACP1 | |
| SCHEMBL8956322 | 0.82 | ALDH1A1 (0.94) | ALDH1A1CYP3A4TAS2R38HSD17B10PTPN7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130053392-A1 | CARBONIC ANHYDRASE INHIBITORS | UNIVERSITETET I OSLO (NO) | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053392-A1 | CARBONIC ANHYDRASE INHIBITORS | CA9, CA2, CA4 | ALDH1A1 682/4885CYP3A4 615/4885TAS2R38 3064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.