Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.36 |
| ▸ | TUBB | P07437 | 5/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.36 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14725539 | 0.85 | EGFR (0.35) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL14722148 | 0.82 | TUBB4A (0.48) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL14721851 | 0.82 | TUBB4A (0.48) | KDM4EALDH1A1HPGDTUBB4ATUBB | |
| SCHEMBL14725261 | 0.82 | TUBB4A (0.49) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL14722766 | 0.81 | TUBB4A (0.47) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL14721807 | 0.81 | KDM4E (0.39) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL14722671 | 0.79 | PDGFRB (0.43) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL14722143 | 0.78 | CCNB2 (0.43) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL14725338 | 0.78 | TUBB4A (0.37) | KDM4EALDH1A1MAPTTUBB4ATUBB | |
| SCHEMBL14725265 | 0.77 | GSK3B (0.38) | KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026942-A1 | TUBULIN BINDING AGENTS | THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN (IE) | 2013-02-28 | — | — | WO | disclosed |