SCHEMBL14725781

SCHEMBL14725781

CC1(C)c2ccccc2-c2cc3c(-c4csc5ccccc45)cc4cc5c(cc(-c6csc7ccccc67)c6cc7c(cc65)C(C)(C)c5ccccc5-7)cc4c3cc21

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.33
CYP2C9 P11712 1/20 0.32
KDM1A O60341 1/20 0.32
ERN1 O75460 2/20 0.31
MAOB P27338 1/20 0.31
MAPT P10636 1/20 0.31
PGK1 P00558 1/20 0.30
PRKCB P05771 1/20 0.30
PRKCA P17252 1/20 0.30
PRKCH P24723 1/20 0.30
PRKCE Q02156 1/20 0.30
PRKCQ Q04759 1/20 0.30
PRKCD Q05655 1/20 0.30
PRKDC P78527 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21180630 0.88 PGR (0.34)
SCHEMBL15460282 0.86 APP (0.33) APPCYP2C9KDM1AERN1MAOB
SCHEMBL15460198 0.85 PRKDC (0.36) APPCYP2C9KDM1AERN1MAOB
SCHEMBL15460329 0.84 MAPT (0.33) APPCYP2C9KDM1AERN1MAOB
SCHEMBL15912249 0.84 KDM4E (0.33) PRKCBPRKCAPRKCHPRKCEPRKCQ
SCHEMBL15460246 0.83 PRKDC (0.33) APPCYP2C9KDM1AERN1MAOB
SCHEMBL14725798 0.82 ALOX5 (0.42) MAPTPRKDC
SCHEMBL14725797 0.79 ALOX5 (0.36) MAPT
SCHEMBL14725783 0.79 APP (0.34) APPCYP2C9ERN1PRKDC
SCHEMBL14725777 0.76 CYP11B1 (0.39) CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9255084-B2 Heterocyclic compound and organic light-emitting device containing the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-02-09 US disclosed
US-20130048955-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CONTAINING THE SAME SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2013-02-28 US disclosed
US-20130048955-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CONTAINING THE SAME SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2013-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130048955-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CONTAINING THE SAME TRPC1, TRPC4, TRPC6 APP 271/4885CYP2C9 152/4885KDM1A 3624/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.