Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.73 |
| ▸ | KIF11 | P52732 | 4/20 | 0.66 |
| ▸ | HTR7 | P34969 | 1/20 | 0.60 |
| ▸ | HTR2B | P41595 | 1/20 | 0.60 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.57 |
| ▸ | AHR | P35869 | 1/20 | 0.55 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GABRP | O00591 | 1/20 | 0.53 |
| ▸ | GABRD | O14764 | 1/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.53 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.53 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.53 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.53 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.53 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.53 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.53 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29377098 | 1.00 | PARP1 (0.73) | PARP1KIF11HTR7HTR2BPDPK1 | |
| SCHEMBL3234597 | 0.91 | PARP1 (0.67) | PARP1KIF11HTR7HTR2BPDPK1 | |
| Pyridine SCHEMBL27428733 | 0.91 | PARP1 (0.61) | PARP1KIF11HTR7HTR2BPDPK1 | |
| SCHEMBL23830045 | 0.90 | PARP1 (0.68) | PARP1KIF11HTR7HTR2BKDM4E | |
| SCHEMBL29620678 | 0.90 | PARP1 (0.68) | PARP1KIF11HTR7HTR2BKDM4E | |
| SCHEMBL70283 | 0.89 | KDM4E (0.60) | PARP1KIF11AHRKDM4EALDH1A1 | |
| SCHEMBL29823892 | 0.89 | KDM4E (0.60) | PARP1KIF11AHRKDM4EALDH1A1 | |
| Carbazole SCHEMBL30782024 | 0.88 | ALDH1A1 (0.61) | PARP1KIF11AHRKDM4EALDH1A1 | |
| Carbazole SCHEMBL28310367 | 0.88 | ALDH1A1 (0.61) | PARP1KIF11AHRKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL6434116 | 0.87 | KDM4E (0.59) | PARP1KIF11HTR7HTR2BAHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114621752-A | Room-temperature phosphorescent waterborne polymer anti-counterfeiting material and preparation method and application thereof | 昆明理工大学 | 2022-06-14 | — | — | CN | claimed |
| CN-102325752-B | Carbazole and carboline kinase inhibitors | BRISTOL MYERS SQUIBB CO | 2015-02-04 | — | — | CN | claimed |
| EP-1599202-A1 | TETRACYCLIC PYRAZOLE DERIVATIVES AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | Pharmacia Italia S.p.A. (IT) | 2005-11-30 | — | — | EP | claimed |
| WO-2004071507-A1 | TETRACYCLIC PYRAZOLE DERIVATIVES AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | PHARMACIA ITALIA S.P.A. (IT) | 2004-08-26 | — | — | WO | claimed |
| WO-1999045926-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AS ANTI-INFLAMMATORY AND IMMUNOMODULATORY AGENTS | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 1999-09-16 | — | — | WO | claimed |
| CN-1088209-A | Heterogeneous ring compound | WELLCOME FOUND (GB) | 1994-06-22 | — | — | CN | claimed |
| JP-61140564-A | — | — | None | — | — | JP | disclosed |
| US-20250346585-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2025-11-13 | — | — | US | disclosed |
| US-20250179046-A1 | SEROTONIN 5-HT2B INHIBITORY COMPOUNDS | ZOETIS SERVICES LLC | 2025-06-05 | — | — | US | disclosed |
| US-12240827-B2 | Serotonin 5-HT2B inhibitory compounds | ZOETIS SERVICES LLC (US) | 2025-03-04 | — | — | US | disclosed |
| CN-119364991-A | Perovskite solar cell and preparation method thereof | 天合光能股份有限公司 | 2025-01-24 | — | — | CN | disclosed |
| CN-119364989-A | Hole transport layer, perovskite solar cell and preparation method thereof | 天合光能股份有限公司 | 2025-01-24 | — | — | CN | disclosed |
| EP-3947360-B1 | SEROTONIN 5-HT2B INHIBITORY COMPOUNDS | ZOETIS SERVICES LLC (US) | 2024-08-07 | — | — | EP | disclosed |
| US-5679694-A | LOW TOXICITY AGAINST NORMAL CELL LINES | THE WELLCOME FOUNDATION LTD. (GB) | 1997-10-21 | — | — | US | disclosed |
| EP-0741729-A1 | ANTITUMOUR TETRACYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-11-13 | — | — | EP | disclosed |
| WO-1995021170-A1 | ANTITUMOUR TETRACYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-08-10 | — | — | WO | disclosed |
| EP-0651750-A1 | TETRACYCLIC COMPOUNDS PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOUR AGENTS | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-05-10 | — | — | EP | disclosed |
| CN-1088209-A | Heterogeneous ring compound | WELLCOME FOUND (GB) | 1994-06-22 | — | — | CN | disclosed |
| JP-S61140564-A | CARBAZOLE DERIVATIVE | MITSUBISHI CHEM IND LTD | 1986-06-27 | — | — | JP | disclosed |
| US-4009181-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIRHEUMATIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1977-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12240827-B2 | Serotonin 5-HT2B inhibitory compounds | HTR2B, HTR1B, HTR5A | PARP1 4048/4885KIF11 3824/4885HTR7 18/4885 |
| US-20250179046-A1 | SEROTONIN 5-HT2B INHIBITORY COMPOUNDS | HTR2B, HTR1B, HTR5A | PARP1 4048/4885KIF11 3824/4885HTR7 18/4885 |
| US-20250346585-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | C5, C1S, C9 | PARP1 714/4885KIF11 3448/4885HTR7 1298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.