Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Carbazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | GPR3 | P46089 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | GLA | P06280 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | PARP1 | P09874 | 1/20 | 0.56 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.56 |
| ▸ | KIF11 | P52732 | 1/20 | 0.54 |
| ▸ | GABRP | O00591 | 1/20 | 0.54 |
| ▸ | GABRD | O14764 | 1/20 | 0.54 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.54 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbazole SCHEMBL30782024 | 1.00 | ALDH1A1 (0.61) | ALDH1A1HSD17B10GPR3KMT2AGLA | |
| Carbazole SCHEMBL27875228 | 0.96 | ALDH1A1 (0.61) | ALDH1A1HSD17B10GPR3KMT2AGLA | |
| SCHEMBL147263 | 0.88 | PARP1 (0.73) | ALDH1A1HSD17B10GPR3KMT2APARP1 | |
| SCHEMBL29377098 | 0.88 | PARP1 (0.73) | ALDH1A1HSD17B10GPR3KMT2APARP1 | |
| SCHEMBL70283 | 0.88 | KDM4E (0.60) | ALDH1A1HSD17B10GPR3KMT2AMEN1 | |
| SCHEMBL29823892 | 0.88 | KDM4E (0.60) | ALDH1A1HSD17B10GPR3KMT2AMEN1 | |
| SCHEMBL27741500 | 0.87 | KDM4E (0.59) | ALDH1A1HSD17B10KMT2AGAAMEN1 | |
| Hydrochloric Acid SCHEMBL6434116 | 0.87 | KDM4E (0.59) | ALDH1A1HSD17B10KMT2AGAAMEN1 | |
| Carbazole SCHEMBL8411559 | 0.86 | ALDH1A1 (0.74) | ALDH1A1HSD17B10GPR3KMT2AGLA | |
| Benzil SCHEMBL28993933 | 0.83 | CES2 (0.61) | ALDH1A1HSD17B10GPR3KMT2AGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110092741-A | The compound of power mutagens color, film and its preparation method and application | 天津师范大学 | 2019-08-06 | — | — | CN | disclosed |