Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | KIF11 | P52732 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | PARP1 | P09874 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | GABRP | O00591 | 1/20 | 0.57 |
| ▸ | GABRD | O14764 | 1/20 | 0.57 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.57 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.57 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.57 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.57 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.57 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29823892 | 1.00 | KDM4E (0.60) | KDM4EALDH1A1KMT2AKIF11MEN1 | |
| SCHEMBL27741500 | 0.98 | KDM4E (0.59) | KDM4EALDH1A1KMT2AKIF11MEN1 | |
| Hydrochloric Acid SCHEMBL6434116 | 0.98 | KDM4E (0.59) | KDM4EALDH1A1KMT2AKIF11MEN1 | |
| SCHEMBL30844878 | 0.90 | KDM4E (0.67) | KDM4EALDH1A1KMT2AKIF11MEN1 | |
| SCHEMBL69604 | 0.90 | KDM4E (0.67) | KDM4EALDH1A1KMT2AKIF11MEN1 | |
| SCHEMBL29377098 | 0.89 | PARP1 (0.73) | KDM4EALDH1A1KMT2AKIF11PARP1 | |
| SCHEMBL147263 | 0.89 | PARP1 (0.73) | KDM4EALDH1A1KMT2AKIF11PARP1 | |
| Carbazole SCHEMBL30782024 | 0.88 | ALDH1A1 (0.61) | KDM4EALDH1A1KMT2AKIF11MEN1 | |
| Carbazole SCHEMBL28310367 | 0.88 | ALDH1A1 (0.61) | KDM4EALDH1A1KMT2AKIF11MEN1 | |
| Hydrochloric Acid SCHEMBL9746959 | 0.88 | KDM4E (0.65) | KDM4EALDH1A1KMT2AKIF11MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113828358-B | Mandelic acid oxidation reaction catalyst and preparation method and application thereof | 万华化学集团股份有限公司 | 2023-12-29 | — | — | CN | claimed |
| CN-114621752-A | Room-temperature phosphorescent waterborne polymer anti-counterfeiting material and preparation method and application thereof | 昆明理工大学 | 2022-06-14 | — | — | CN | claimed |
| CN-113828358-A | Mandelic acid oxidation reaction catalyst, preparation method and application thereof | 万华化学集团股份有限公司 | 2021-12-24 | — | — | CN | claimed |
| CN-113651452-A | Preparation method and application of porous metal organic framework material | 清华大学 | 2021-11-16 | — | — | CN | claimed |
| CN-104628756-B | 2, 2-difluoro-4, 6-di (N-ethyl carbazole-3) -2H-1, 3, 2-dioxin borane compound and preparation method and application thereof | 中国科学院理化技术研究所 | 2017-05-17 | — | — | CN | claimed |
| CN-104628756-A | 2, 2-difluoro-4, 6-di (N-ethyl carbazole-3) -2H-1,3, 2-dioxin borane compound and preparation method and application thereof | CHINESE ACAD TECH INST PHYSICS | 2015-05-20 | — | — | CN | claimed |
| CN-102325752-B | Carbazole and carboline kinase inhibitors | BRISTOL MYERS SQUIBB CO | 2015-02-04 | — | — | CN | claimed |
| US-8129376-B2 | Piperidine derivatives as inhibitors of stearoyl-CoA desaturase | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2012-03-06 | — | — | US | claimed |
| CN-101440281-B | Benzocarbazole intercalation hydrotalcite composite luminous material and preparing process thereof | UNIV BEIJING CHEMICAL | 2011-11-23 | — | — | CN | claimed |
| WO-2010075356-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-07-01 | — | — | WO | claimed |
| WO-2009117676-A2 | NOVEL PIPERIDINE DERIVATIVES AS INHIBITORS OF STEAROYL-COA DESATURASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2009-09-24 | — | — | WO | claimed |
| US-20090239810-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2009-09-24 | — | — | US | claimed |
| WO-2009106597-A1 | USE OF LHRH ANTAGONISTS AT NON-CASTRATING DOSES | ÆTERNA ZENTARIS GMBH (DE) | 2009-09-03 | — | — | WO | claimed |
| CN-101440281-A | Benzocarbazole intercalation hydrotalcite composite luminous material and preparing process thereof | UNIV BEIJING CHEMICAL (CN) | 2009-05-27 | — | — | CN | claimed |
| WO-2008132153-A1 | NOVEL TETRAHYDROCARBAZOLE DERIVATIVES AS LIGANDS OF G-PROTEIN COUPLED RECEPTORS | ÆTERNA ZENTARIS GMBH (DE) | 2008-11-06 | — | — | WO | claimed |
| WO-2008107446-A1 | USE OF LHRH ANTAGONISTS FOR THE TREATMENT OF LOWER URINARY TRACT SYMPTOMS, IN PARTICULAR OVERACTIVE BLADDER AND/OR DETRUSOR OVERACTIVITY | ÆTERNA ZENTARIS GMBH (DE) | 2008-09-12 | — | — | WO | claimed |
| EP-1599202-A1 | TETRACYCLIC PYRAZOLE DERIVATIVES AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | Pharmacia Italia S.p.A. (IT) | 2005-11-30 | — | — | EP | claimed |
| WO-2004071507-A1 | TETRACYCLIC PYRAZOLE DERIVATIVES AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | PHARMACIA ITALIA S.P.A. (IT) | 2004-08-26 | — | — | WO | claimed |
| EP-0064317-B1 | PYRROLO(2,3-D)CARBAZOLE DERIVATIVES, PREPARATION THEREOF AND THEIR THERAPEUTICAL USE | OMNICHEM Société anonyme (BE) | 1986-02-26 | — | — | EP | claimed |
| EP-0064317-A2 | Pyrrolo(2,3-d)carbazole derivatives, preparation thereof and their therapeutical use | OMNICHEM Société anonyme (BE) | 1982-11-10 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239810-A1 | NOVEL PIPERAZINE DERIVATIVES AS INHIBITORS OF STEAROYL-CoA DESATURASE | SCD, SCD5, FADS2 | KDM4E 375/4885ALDH1A1 784/4885KMT2A 1352/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.