SCHEMBL14727167

SCHEMBL14727167

C=Cc1ccc(N(c2ccccc2)c2ccc(CCCCc3ccc(N(c4ccc(C=C)cc4)c4ccc(C=C)cc4)cc3)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
TSHR P16473 1/20 0.43
KCNH2 Q12809 2/20 0.41
CHRM2 P08172 1/20 0.41
HTR1A P08908 1/20 0.41
ADRA2A P08913 1/20 0.41
CHRM1 P11229 1/20 0.41
DRD1 P21728 1/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A4 P31645 1/20 0.41
ADRA1A P35348 1/20 0.41
OPRM1 P35372 1/20 0.41
DRD3 P35462 1/20 0.41
SLC6A3 Q01959 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
MAOB P27338 2/20 0.40
SIGMAR1 Q99720 3/20 0.40
KDM4E B2RXH2 1/20 0.38
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14727132 0.93 ALDH1A1 (0.46) ALDH1A1TSHRKCNH2CHRM2HTR1A
SCHEMBL14727180 0.93 ALDH1A1 (0.44) ALDH1A1TSHRCHRM2ADRA2ACHRM1
SCHEMBL14727152 0.92 HSD11B1 (0.43) ALDH1A1TSHRKCNH2CHRM2HTR1A
SCHEMBL15505254 0.86 L3MBTL1 (0.51) SIGMAR1TDP1L3MBTL1
SCHEMBL14732691 0.86 L3MBTL1 (0.51) SIGMAR1TDP1L3MBTL1
SCHEMBL12925398 0.86 ALDH1A1 (0.46) ALDH1A1TSHRMEN1KMT2AKDM4E
SCHEMBL15502206 0.85 L3MBTL1 (0.44) ALDH1A1TSHRKCNH2MEN1KMT2A
SCHEMBL17545456 0.85 ALDH1A1 (0.48) ALDH1A1TSHRTDP1AOC3
SCHEMBL14727191 0.85 ALDH1A1 (0.48) ALDH1A1TSHRTDP1AOC3
SCHEMBL152443 0.85 ALDH1A1 (0.54) ALDH1A1TSHRMAOBSIGMAR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8663883-B2 Charge-transporting film, photoelectric conversion device, electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2014-03-04 US disclosed
US-8663883-B2 Charge-transporting film, photoelectric conversion device, electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2014-03-04 US disclosed
US-20130052570-A1 CHARGE-TRANSPORTING FILM, PHOTOELECTRIC CONVERSION DEVICE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2013-02-28 US disclosed
US-20130052570-A1 CHARGE-TRANSPORTING FILM, PHOTOELECTRIC CONVERSION DEVICE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2013-02-28 US disclosed