SCHEMBL14727152

SCHEMBL14727152

C=Cc1ccc(N(c2ccc(CCCCc3ccc(N(c4ccc(C=C)cc4)c4ccc(-c5ccccc5)cc4)cc3)cc2)c2ccc(-c3ccccc3)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.43
HDAC2 Q92769 2/20 0.41
HDAC1 Q13547 1/20 0.40
ALDH1A1 P00352 1/20 0.39
TSHR P16473 1/20 0.39
POLB P06746 1/20 0.38
FDFT1 P37268 2/20 0.38
FFAR1 O14842 1/20 0.38
CHRM2 P08172 1/20 0.38
HTR1A P08908 1/20 0.38
ADRA2A P08913 1/20 0.38
CHRM1 P11229 1/20 0.38
DRD1 P21728 1/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
ADRA1A P35348 1/20 0.38
OPRM1 P35372 1/20 0.38
DRD3 P35462 1/20 0.38
SLC6A3 Q01959 1/20 0.38
KCNH2 Q12809 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14727148 0.94 ALDH1A1 (0.42) HSD11B1ALDH1A1TSHRPOLBFFAR1
SCHEMBL14727167 0.92 ALDH1A1 (0.43) HSD11B1ALDH1A1TSHRCHRM2HTR1A
SCHEMBL14727180 0.88 ALDH1A1 (0.44) ALDH1A1TSHRCHRM2ADRA2ACHRM1
SCHEMBL14727129 0.88 L3MBTL1 (0.40) HSD11B1HDAC2HDAC1FFAR1MGLL
SCHEMBL14727201 0.88 IDO1 (0.36) HSD11B1TSHRPOLBFFAR1
SCHEMBL14732704 0.87 NAAA (0.43) HSD11B1
SCHEMBL12084927 0.87 ALDH1A1 (0.52) HDAC2ALDH1A1TSHRPOLBMGLL
SCHEMBL10160368 0.87 ALDH1A1 (0.52) HDAC2ALDH1A1TSHRPOLBMGLL
SCHEMBL10160364 0.87 ALDH1A1 (0.52) HDAC2ALDH1A1TSHRPOLBMGLL
SCHEMBL5406679 0.87 ALDH1A1 (0.52) HDAC2ALDH1A1TSHRPOLBMGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8663883-B2 Charge-transporting film, photoelectric conversion device, electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2014-03-04 US disclosed
US-8663883-B2 Charge-transporting film, photoelectric conversion device, electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2014-03-04 US disclosed
US-20130052570-A1 CHARGE-TRANSPORTING FILM, PHOTOELECTRIC CONVERSION DEVICE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2013-02-28 US disclosed
US-20130052570-A1 CHARGE-TRANSPORTING FILM, PHOTOELECTRIC CONVERSION DEVICE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2013-02-28 US disclosed