SCHEMBL14727253

SCHEMBL14727253

CCCc1ccc(N(c2ccc(/C=C/C=C/c3ccc(C)cc3)cc2)c2ccc(/C=C/C=C/c3ccc(C)cc3)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.43
CNR2 P34972 1/20 0.38
LPL P06858 1/20 0.38
LIPG Q9Y5X9 1/20 0.38
CYP1A2 P05177 1/20 0.37
CYP2A6 P11509 1/20 0.37
TAAR1 Q96RJ0 1/20 0.37
NFE2L2 Q16236 1/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36
MEN1 O00255 1/20 0.35
APOBEC3A P31941 1/20 0.35
RAB9A P51151 1/20 0.35
KMT2A Q03164 1/20 0.35
APOBEC3G Q9HC16 1/20 0.35
RELA Q04206 1/20 0.34
CA1 P00915 1/20 0.34
MAPT P10636 1/20 0.34
LMNA P02545 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18680248 1.00 APP (0.43) APPCNR2LPLLIPGCYP1A2
SCHEMBL18680233 0.94 CNR2 (0.44) APPCNR2RELAMAPTLMNA
SCHEMBL18680239 0.94 CNR2 (0.44) APPCNR2RELAMAPTLMNA
SCHEMBL18680258 0.90 CYP3A4 (0.42) APPCNR2LPLLIPGCYP1A2
SCHEMBL14727249 0.87 MAOB (0.47) APPLPLLIPGRELALMNA
SCHEMBL19380026 0.86 NFE2L2 (0.45) APPCYP1A2CYP2A6TAAR1NFE2L2
SCHEMBL13049996 0.86 APP (0.56) APPCYP2A6NFE2L2MEN1APOBEC3A
SCHEMBL973801 0.86 LPL (0.48) CNR2LPLLIPGCYP1A2CYP2A6
SCHEMBL14981808 0.86 LPL (0.48) CNR2LPLLIPGCYP1A2CYP2A6
SCHEMBL14490239 0.86 APP (0.56) APPCYP2A6NFE2L2MEN1APOBEC3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11287756-B2 Positive charging electrophotographic photoreceptor, electrophotographic cartridge and image forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2022-03-29 US disclosed
US-9977354-B2 Coating liquid for electrophotographic photoreceptor production, electrophotographic photoreceptor, and image formation apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2018-05-22 US disclosed
US-20170090308-A1 COATING LIQUID FOR ELECTROPHOTOGRAPHIC PHOTORECEPTOR PRODUCTION, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMATION APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2017-03-30 US disclosed
US-20170090308-A1 COATING LIQUID FOR ELECTROPHOTOGRAPHIC PHOTORECEPTOR PRODUCTION, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMATION APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2017-03-30 US disclosed
US-8709689-B2 Electrophotographic photoreceptor, image-forming apparatus, and electrophotographic cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2014-04-29 US disclosed
US-8709689-B2 Electrophotographic photoreceptor, image-forming apparatus, and electrophotographic cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2014-04-29 US disclosed
US-20130052574-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2013-02-28 US disclosed
US-20130052574-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2013-02-28 US disclosed