SCHEMBL14727633

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14727523	0.90	CYP1A2 (0.70)	MEN1ALDH1A1CYP1A2GLACYP3A4
	SCHEMBL16183628	0.84	GBA1 (0.60)	MEN1ALDH1A1CYP1A2GLACYP3A4
	SCHEMBL20609337	0.82	ALDH1A1 (1.00)	MEN1ALDH1A1CYP1A2GLACYP3A4
	SCHEMBL2162585	0.80	CYP11B1 (0.49)	MEN1ALDH1A1CYP1A2GLACYP3A4
	SCHEMBL14727632	0.80	CYP1A2 (0.50)	MEN1ALDH1A1CYP1A2GLACYP3A4
	SCHEMBL14358473	0.80	CYP11B1 (0.49)	MEN1ALDH1A1CYP1A2GLACYP3A4
	SCHEMBL16183627	0.80	CYP1A2 (0.62)	MEN1ALDH1A1CYP1A2GLACYP3A4
	SCHEMBL14358804	0.80	MAPT (0.56)	MEN1ALDH1A1CYP1A2GLACYP3A4
	SCHEMBL14359091	0.80	CYP1A2 (0.70)	MEN1ALDH1A1CYP1A2CYP3A4CYP2D6
	SCHEMBL14474589	0.77	MEN1 (0.59)	MEN1ALDH1A1CYP1A2GLACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.