SCHEMBL14727869

SCHEMBL14727869

CCOC(=O)COCC(COC(=O)C12CC3CC(C1)C(OC(=O)C(C)(C)C)C(C3)C2)OCC(=O)OCC

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 1/20 0.38
HSD11B1 P28845 2/20 0.32
PKM P14618 1/20 0.31
EPHX2 P34913 1/20 0.31
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
KMT2A Q03164 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14727867 0.81 PRKCA (0.40) PRKCAHSD11B1PKMMEN1ALDH1A1
SCHEMBL14727763 0.80 PRKCA (0.35) PRKCA
SCHEMBL14727768 0.79 PRKCA (0.35) PRKCA
SCHEMBL14727850 0.77 PRKCA (0.45) PRKCAHSD11B1PKMMEN1ALDH1A1
SCHEMBL14731197 0.76 PRKCA (0.33) PRKCA
SCHEMBL14727852 0.75 PRKCA (0.45) PRKCAHSD11B1PKMMEN1ALDH1A1
SCHEMBL14731168 0.75 PRKCA (0.33) PRKCA
SCHEMBL14700422 0.72 PKM (0.38) PRKCAHSD11B1PKMMEN1ALDH1A1
SCHEMBL14700418 0.69 PKM (0.35) PRKCAHSD11B1PKM
SCHEMBL14700412 0.69 PKM (0.46) PRKCAHSD11B1PKMMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8741544-B2 Salt, photoresist composition and method for producing photoresist pattern SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-06-03 US disclosed
US-20130052588-A1 SALT, PHOTORESIST COMPOSITION AND METHOD FOR PRODUCING PHOTORESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130052588-A1 SALT, PHOTORESIST COMPOSITION AND METHOD FOR PRODUCING PHOTORESIST PATTERN RER1, COL1A1, H1-0 PRKCA 2755/4885HSD11B1 2714/4885PKM 4340/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.