Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 8/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 7/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14728405 | 0.90 | PIK3CD (0.35) | PIK3CBPIK3CDPIK3CAPIK3CG | |
| SCHEMBL14728568 | 0.87 | USP2 (0.33) | PIK3CBPIK3CD | |
| SCHEMBL14728235 | 0.84 | ADCY10 (0.31) | CCR2 | |
| SCHEMBL14728601 | 0.81 | PIK3CB (0.34) | CCR2CCR5PIK3CBPIK3CDPIK3CA | |
| SCHEMBL14728375 | 0.78 | PIK3CB (0.38) | CCR2CCR5PIK3CBPIK3CDPIK3CA | |
| SCHEMBL14728328 | 0.76 | PIK3CB (0.55) | PIK3CBPIK3CDPIK3CAPIK3CG | |
| SCHEMBL14720301 | 0.74 | PIK3CB (0.53) | CCR2CCR5PIK3CBPIK3CDPIK3CA | |
| SCHEMBL14728548 | 0.72 | PIK3CB (0.32) | PIK3CBPIK3CDPIK3CG | |
| Acetic Acid SCHEMBL14720443 | 0.70 | PIK3CD (0.51) | PIK3CBPIK3CDPIK3CAPIK3CGP2RX7 | |
| SCHEMBL14728354 | 0.69 | PIK3CB (0.45) | PIK3CBPIK3CDPIK3CAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013028263-A1 | PYRAZOLOPYRIMIDINE DERIVATIVES AS PI3 KINASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2013-02-28 | — | — | WO | disclosed |