Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11406153 | 0.95 | ATM (0.43) | KMT2AMEN1ATMTDP1MAPT | |
| SCHEMBL14728395 | 0.94 | CYP3A4 (0.50) | KMT2AMEN1TDP1CYP3A4MAPT | |
| SCHEMBL11405200 | 0.88 | ALOX15 (0.50) | ATMTDP1CYP3A4MAPTALDH1A1 | |
| SCHEMBL247585 | 0.82 | TDP1 (0.58) | KMT2AMEN1ATMTDP1MAPT | |
| SCHEMBL10596262 | 0.81 | KMT2A (0.58) | KMT2AMEN1ATMTDP1CYP3A4 | |
| SCHEMBL247541 | 0.80 | ATM (0.46) | KMT2AMEN1ATMTDP1MAPT | |
| SCHEMBL14728392 | 0.80 | PTGS1 (0.37) | KMT2AMEN1ATMTDP1MAPT | |
| SCHEMBL2164486 | 0.76 | CA2 (0.46) | KMT2AATMTDP1CYP3A4MAPT | |
| SCHEMBL1624312 | 0.75 | MAPT (0.49) | KMT2AMEN1ATMTDP1CYP3A4 | |
| SCHEMBL20514295 | 0.75 | MAPT (0.50) | KMT2AMEN1ATMTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8669315-B2 | Polycarbonate compositions and methods for the manufacture and use thereof | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2014-03-11 | — | — | US | disclosed |
| US-20130053487-A1 | POLYCARBONATE COMPOSITIONS AND METHODS FOR THE MANUFACTURE AND USE THEREOF | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2013-02-28 | — | — | US | disclosed |