Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.49 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | BLM | P54132 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14728832 | 0.82 | CHRM5 (0.49) | RAB9ANPC1BLMPKMCYP1A2 | |
| SCHEMBL14728838 | 0.81 | MAPT (0.54) | RAB9ANPC1BLMPKMMEN1 | |
| SCHEMBL14728827 | 0.81 | KMT2A (0.41) | RAB9ANPC1BLMPKMMAPK1 | |
| SCHEMBL14728840 | 0.75 | MAOB (0.43) | RAB9ANPC1BLMPKMMEN1 | |
| SCHEMBL11415462 | 0.73 | RAB9A (0.51) | RAB9ANPC1BLMPKMCYP1A2 | |
| SCHEMBL14728816 | 0.73 | KDM4E (0.44) | RAB9ABLMPKMMEN1KMT2A | |
| SCHEMBL11415466 | 0.73 | RAB9A (0.51) | RAB9ANPC1BLMPKMCYP1A2 | |
| SCHEMBL14728836 | 0.72 | KMT2A (0.44) | RAB9ANPC1BLMPKMMEN1 | |
| SCHEMBL14728791 | 0.72 | PKM (0.54) | RAB9ANPC1BLMPKMMEN1 | |
| SCHEMBL14728822 | 0.69 | APP (0.46) | RAB9ANPC1PKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026357-A1 | PREPARATION METHOD OF IMIDAZOLE DERIVATIVES | 北京欧博方医药科技有限公司 (CN) | 2013-02-28 | — | — | WO | disclosed |