Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | S100B | P04271 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14728791 | 0.83 | PKM (0.54) | GAAL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL14728818 | 0.81 | MEN1 (0.39) | APPGAAL3MBTL1ALDH1A1MEN1 | |
| SCHEMBL14728836 | 0.80 | KMT2A (0.44) | L3MBTL1ALDH1A1MEN1KMT2APTGS2 | |
| SCHEMBL14728838 | 0.79 | MAPT (0.54) | GAAL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL20871770 | 0.76 | S100B (0.70) | APPGAAL3MBTL1S100BALDH1A1 | |
| SCHEMBL28112599 | 0.76 | S100B (0.70) | APPGAAL3MBTL1S100BALDH1A1 | |
| SCHEMBL14728840 | 0.73 | MAOB (0.43) | APPL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL14728827 | 0.73 | KMT2A (0.41) | GAAL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL10733285 | 0.69 | S100B (0.82) | GAAL3MBTL1S100BALDH1A1MEN1 | |
| SCHEMBL10412841 | 0.69 | S100B (0.82) | GAAL3MBTL1S100BALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026357-A1 | PREPARATION METHOD OF IMIDAZOLE DERIVATIVES | 北京欧博方医药科技有限公司 (CN) | 2013-02-28 | — | — | WO | disclosed |