Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14728822 | 0.81 | APP (0.46) | MEN1KMT2AMAPTALDH1A1PKM | |
| SCHEMBL14728791 | 0.76 | PKM (0.54) | MEN1KMT2AADRA2AADRA2BADRA2C | |
| SCHEMBL14728836 | 0.76 | KMT2A (0.44) | MEN1KMT2AADRA2AADRA2BADRA2C | |
| SCHEMBL14728838 | 0.76 | MAPT (0.54) | MEN1KMT2AADRA2AADRA2BADRA2C | |
| SCHEMBL14728827 | 0.72 | KMT2A (0.41) | MEN1KMT2AADRA2AADRA2BADRA2C | |
| SCHEMBL3724578 | 0.70 | SCN5A (0.44) | KCNH2SCN1ASCN5ASCN9ASCN2A | |
| SCHEMBL4470732 | 0.70 | THRB (0.51) | MEN1KMT2AKCNH2SCN1ASCN5A | |
| SCHEMBL14728840 | 0.70 | MAOB (0.43) | MEN1KMT2AADRA2AADRA2BADRA2C | |
| SCHEMBL21729900 | 0.69 | MAPT (0.49) | MEN1KMT2AKDM4EMAPTHTT | |
| SCHEMBL220074 | 0.69 | MAPT (0.47) | MEN1KMT2AKCNH2SCN1ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026357-A1 | PREPARATION METHOD OF IMIDAZOLE DERIVATIVES | 北京欧博方医药科技有限公司 (CN) | 2013-02-28 | — | — | WO | disclosed |