SCHEMBL14729299

SCHEMBL14729299

CC(C)(C)OC(=O)CC[C@H](NC(=O)[C@H](CC(=O)OC(C)(C)C)NC(=O)CN=[N+]=[N-])C(=O)OC(C)(C)C

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.34
▸ KMT2A Q03164 2/20 0.33
▸ POLB P06746 1/20 0.33
▸ HDAC8 Q9BY41 1/20 0.32
▸ CYP2D6 P10635 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18145426 1.00 L3MBTL1 (0.34) L3MBTL1KMT2APOLBHDAC8CYP2D6
SCHEMBL14729276 0.90 L3MBTL1 (0.36) L3MBTL1KMT2APOLBHDAC8
SCHEMBL18145848 0.90 L3MBTL1 (0.36) L3MBTL1KMT2APOLBHDAC8
SCHEMBL20341539 0.82 L3MBTL1 (0.39) L3MBTL1KMT2APOLBHDAC8CYP2D6
SCHEMBL18161562 0.79 KMT2A (0.41) L3MBTL1KMT2APOLBHDAC8
SCHEMBL14729303 0.79 KMT2A (0.41) L3MBTL1KMT2APOLBHDAC8
SCHEMBL18145473 0.79 KMT2A (0.41) L3MBTL1KMT2APOLBHDAC8
SCHEMBL22733296 0.78 L3MBTL1 (0.34) L3MBTL1KMT2APOLBHDAC8CYP2D6
SCHEMBL18161564 0.78 TDP1 (0.39) KMT2APOLB
SCHEMBL15510866 0.78 TDP1 (0.39) KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12583887-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2026-03-24 — — US disclosed
US-12559521-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2026-02-24 — — US disclosed
US-20240425547-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2024-12-26 — — US disclosed
US-20240409580-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2024-12-12 — — US disclosed
US-12139554-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2024-11-12 — — US disclosed
US-12122851-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2024-10-22 — — US disclosed
US-20210032286-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-02-04 — — US disclosed
US-20210032286-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-02-04 — — US disclosed
US-20210024574-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-01-28 — — US disclosed
US-20210024574-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-01-28 — — US disclosed
US-20200377549-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2020-12-03 — — US disclosed
US-20200377549-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2020-12-03 — — US disclosed
US-20180258134-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2018-09-13 — — US disclosed
US-10011632-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2018-07-03 — — US disclosed
US-10011632-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2018-07-03 — — US disclosed
US-10011632-B2 PSMA imaging agents SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2018-07-03 — — US disclosed
US-20160304555-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2016-10-20 — — US disclosed
US-20160304555-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2016-10-20 — — US disclosed
US-20160304555-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2016-10-20 — — US disclosed
WO-2013028664-A1 PSMA IMAGING AGENTS SIEMENS MEDICAL SOLUTIONS USA, INC. (US) 2013-02-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240425547-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 L3MBTL1 4197/4885KMT2A 3251/4885POLB 3330/4885
US-20180258134-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 L3MBTL1 4197/4885KMT2A 3251/4885POLB 3330/4885
US-20240409580-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 L3MBTL1 4197/4885KMT2A 3251/4885POLB 3330/4885
US-12559521-B2 PSMA imaging agents KLK3, PSMA1, PSMA6 L3MBTL1 2844/4885KMT2A 2592/4885POLB 3769/4885
US-12139554-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 L3MBTL1 4197/4885KMT2A 3251/4885POLB 3330/4885
US-20200377549-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 L3MBTL1 4197/4885KMT2A 3251/4885POLB 3330/4885
US-12583887-B2 PSMA imaging agents KLK3, PSMA3, PSMA1 L3MBTL1 3753/4885KMT2A 2897/4885POLB 3904/4885
US-20210032286-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 L3MBTL1 4197/4885KMT2A 3251/4885POLB 3330/4885
US-10011632-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 L3MBTL1 4197/4885KMT2A 3251/4885POLB 3330/4885
US-12122851-B2 PSMA imaging agents FOLH1, KLK3, PSMA2 L3MBTL1 4197/4885KMT2A 3251/4885POLB 3330/4885
US-20210024574-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 L3MBTL1 4197/4885KMT2A 3251/4885POLB 3330/4885
US-20160304555-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 L3MBTL1 4197/4885KMT2A 3251/4885POLB 3330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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