SCHEMBL22733296

SCHEMBL22733296

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nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.34
▸ KMT2A Q03164 2/20 0.33
▸ POLB P06746 1/20 0.33
▸ HDAC8 Q9BY41 1/20 0.32
▸ CYP2D6 P10635 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22733317 0.89 KMT2A (0.34) L3MBTL1KMT2APOLBHDAC8
SCHEMBL14729276 0.85 L3MBTL1 (0.36) L3MBTL1KMT2APOLBHDAC8
SCHEMBL18145848 0.85 L3MBTL1 (0.36) L3MBTL1KMT2APOLBHDAC8
SCHEMBL14729303 0.83 KMT2A (0.41) L3MBTL1KMT2APOLBHDAC8
SCHEMBL18161562 0.83 KMT2A (0.41) L3MBTL1KMT2APOLBHDAC8
SCHEMBL18145473 0.83 KMT2A (0.41) L3MBTL1KMT2APOLBHDAC8
SCHEMBL18145426 0.78 L3MBTL1 (0.34) L3MBTL1KMT2APOLBHDAC8CYP2D6
SCHEMBL14729299 0.78 L3MBTL1 (0.34) L3MBTL1KMT2APOLBHDAC8CYP2D6
SCHEMBL21541230 0.77 FOLH1 (0.38) L3MBTL1KMT2APOLBHDAC8
SCHEMBL16094006 0.77 FOLH1 (0.38) L3MBTL1KMT2APOLBHDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210032286-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-02-04 — — US disclosed
US-20210024574-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2021-01-28 — — US disclosed
US-20200377549-A1 PSMA Imaging Agents SIEMENS MEDICAL SOLUTIONS USA, INC. 2020-12-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200377549-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 L3MBTL1 4197/4885KMT2A 3251/4885POLB 3330/4885
US-20210032286-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 L3MBTL1 4197/4885KMT2A 3251/4885POLB 3330/4885
US-20210024574-A1 PSMA Imaging Agents FOLH1, KLK3, PSMA2 L3MBTL1 4197/4885KMT2A 3251/4885POLB 3330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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