Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11920352 | 0.85 | TSHR (0.44) | TSHRPRKCA | |
| SCHEMBL890588 | 0.85 | TSHR (0.49) | TSHRHCAR2 | |
| SCHEMBL22417596 | 0.81 | TSHR (0.40) | TSHRPRKCA | |
| SCHEMBL14729534 | 0.80 | TSHR (0.37) | TSHRPRKCA | |
| SCHEMBL15894729 | 0.80 | TSHR (0.44) | TSHRPRKCA | |
| SCHEMBL10168267 | 0.79 | TSHR (0.45) | TSHRHCAR2 | |
| SCHEMBL29394650 | 0.79 | TSHR (0.45) | TSHRHCAR2 | |
| SCHEMBL15894727 | 0.79 | TSHR (0.45) | TSHRHCAR2 | |
| SCHEMBL15894733 | 0.78 | ALDH1A1 (0.36) | TSHRPRKCA | |
| SCHEMBL18269755 | 0.77 | TSHR (0.46) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2747737-B1 | DENTAL COMPOSITIONS COMPRISING ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES CO (US) | 2019-09-25 | — | — | EP | disclosed |
| US-9907733-B2 | Dental compositions comprising addition-fragmentation agents | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-03-06 | — | — | US | disclosed |
| US-9907733-B2 | Dental compositions comprising addition-fragmentation agents | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2018-03-06 | — | — | US | disclosed |
| US-20160008234-A1 | DENTAL COMPOSITIONS COMPRISING ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-01-14 | — | — | US | disclosed |
| US-20160008234-A1 | DENTAL COMPOSITIONS COMPRISING ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-01-14 | — | — | US | disclosed |
| US-8980969-B2 | Addition-fragmentation agents | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-03-17 | — | — | US | disclosed |
| US-8980969-B2 | Addition-fragmentation agents | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-03-17 | — | — | US | disclosed |
| US-20140206788-A1 | ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-07-24 | — | — | US | disclosed |
| US-20140206788-A1 | ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-07-24 | — | — | US | disclosed |
| WO-2013028397-A2 | DENTAL COMPOSITIONS COMPRISING ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-02-28 | — | — | WO | disclosed |
| WO-2013028401-A1 | ADDITION-FRAGMENTATION AGENTS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160008234-A1 | DENTAL COMPOSITIONS COMPRISING ADDITION-FRAGMENTATION AGENTS | RAD51, TUBA8, ERCC4 | TSHR 4850/4885HCAR2 3987/4885PRKCA 3538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.